GET4 and DUSP21

Data Source:
BioGRID (two hybrid)

		GET4	DUSP21
Description		guided entry of tail-anchored proteins factor 4	dual specificity phosphatase 21
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol BAT3 Complex	Nucleus Cytoplasm Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane
	Molecular Function	Protein Binding Chaperone Binding	Protein Tyrosine Phosphatase Activity Protein Binding MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Protein Insertion Into ER Membrane Cytoplasmic Sequestering Of Protein Tail-anchored Membrane Protein Insertion Into ER Membrane Maintenance Of Unfolded Protein Involved In ERAD Pathway	Inactivation Of MAPK Activity Peptidyl-tyrosine Dephosphorylation
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		PR interval ( 32439900)
Interacting Genes		29 interacting genes: AKT1 ATP5PD BAG6 C1orf109 CAPNS1 CDKN1A CEP126 DUSP21 EEF1G ENKD1 FBN1 FLYWCH2 GET3 GIT2 KAT5 KIFC2 KRTAP9-3 NUP85 PLK1 PRKAB2 PRKCSH PTMS SDCBP SEC61B SNCAIP SOD2 TMEM256 TTR UBAC2	33 interacting genes: APP ATP23 BPIFA1 CPNE7 CTBP2 EPHA3 EPHA5 ERBB3 ERBB4 EYA2 FAAP20 GET4 GORASP2 IGF1R KLHL20 KRT33B KRTAP11-1 MAP2K5 MYO15B OIP5 POU4F3 PTK7 RFX6 RGS2 ROR1 ROR2 SUOX TEX11 TOX3 TRAF1 UBQLN2 USP2 ZMAT1
Entrez ID		51608	63904
HPRD ID		12909	06494
Ensembl ID		ENSG00000239857	ENSG00000189037
Uniprot IDs		Q7L5D6	Q9H596
PDB IDs		6AU8
Enriched GO Terms of Interacting Partners?
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