PDGFRA and TGFBR2

  • Data Source:
  • BioGRID (two hybrid)

PDGFRA

TGFBR2

Description platelet derived growth factor receptor alpha transforming growth factor beta receptor 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Breast cancer ( 29059683 23535729)
  • Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Estimated glomerular filtration rate ( 31152163)
  • Heel bone mineral density ( 30598549)
  • Metabolite levels ( 23823483)
  • Migraine ( 22683712 27322543)
  • Migraine - clinic-based ( 23793025)
  • Night sleep phenotypes ( 27126917)
  • Postprandial triglyceride response ( 32603185)
  • Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab) ( 25117820)
  • Systolic blood pressure ( 30224653)
  • Tonometry ( 17903302)
Interacting Genes 64 interacting genes: AKT1 ARNT AURKA BECN1 CAV1 CAV3 CBL CCND2 CD44 CDK4 CDK6 CDKN2A CDKN2B CDKN2C CRK CRKL EGFR EPHA2 ERBB2 ERBB3 FBXO25 FGFR4 FZR1 GRB14 GRM1 HGF ITGAV ITGB3 JAK1 KASH5 KDELR2 LATS2 MAP2K5 MYC NF2 PDGFA PDGFB PDGFC PDGFRB PIK3CA PIK3R1 PLCG1 PLPP6 PRMT5 PTPN11 RAF1 SHB SHF SLC9A3R1 SMURF1 SNX2 SNX4 SNX6 SRPK1 STAT1 STAT3 STAT5A STAT5B STK11 TERT TGFBR2 TP53 TTYH2 ULBP2 50 interacting genes: ACVR1 ACVRL1 AP2B1 APP ARHGEF6 ARHGEF7 CCNB1 CCNB2 CD44 CDK1 CLU CTNNB1 DAB2 DAXX DYNLT4 EIF3I ENG FANCC GOPC KCNK18 MAP2K1 NRP1 OSR1 PAK1 PDGFRA PIK3R1 PIK3R2 PML PPP2CB PSMD14 RCVRN SMAD3 SMAD4 SMAD7 SNX6 STRAP TDGF1 TERT TGFB1 TGFB1I1 TGFB2 TGFB3 TGFBR1 TGFBR3 TGFBRAP1 TRAP1 TRMO TSSK1B ZFYVE9 ZNF510
Entrez ID 5156 7048
HPRD ID 01429 01823
Ensembl ID ENSG00000134853 ENSG00000163513
Uniprot IDs P16234 A3QNQ0 D2JYI1 P37173
PDB IDs 1GQ5 5GRN 5K5X 6A32 6JOI 6JOJ 6JOK 6JOL 1KTZ 1M9Z 1PLO 2PJY 3KFD 4P7U 4XJJ 5E8V 5E8Y 5E91 5E92 5QIN 5TX4 5TY4
Enriched GO Terms of Interacting Partners?
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