SPOUT1 and MIRLET7C

Data Source:
BioGRID (unspecified method)

		SPOUT1	MIRLET7C
Description		SPOUT domain containing methyltransferase 1	microRNA let-7c
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Cytoplasm Spindle Pole Centrosome Mitotic Spindle	Extracellular Space Nucleus Cytoplasm Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity MiRNA Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Cell Cycle Posttranscriptional Regulation Of Gene Expression Methylation Production Of MiRNAs Involved In Gene Silencing By MiRNA Cell Division Maintenance Of Centrosome Location	Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-8 Production Gene Silencing By MiRNA Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT
Pathways
Drugs
Diseases
GWAS
Interacting Genes		51 interacting genes: CSNK2B INCA1 MIR1-1 MIR106A MIR106B MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR34A MIR34B MIR429 MIR7-1 MIR9-1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PLK1	96 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B ATXN2L C1QBP CHERP CPSF1 CPSF6 DARS1 DDX1 DDX21 DDX3X DHX36 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PTBP1 PTBP3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RBM4B RBMS2 RTCA RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TENT2 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		51490	406885
HPRD ID		12935
Ensembl ID		ENSG00000198917	ENSG00000199030
Uniprot IDs		Q5T280
PDB IDs		4RG1
Enriched GO Terms of Interacting Partners?
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