AIG1 and FZD7

Data Source:
BioGRID (two hybrid)

		AIG1	FZD7
Description		androgen induced 1	frizzled class receptor 7
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane
	Molecular Function	Protein Binding Hydrolase Activity	G Protein-coupled Receptor Activity Frizzled Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Wnt-protein Binding PDZ Domain Binding Wnt-activated Receptor Activity
	Biological Process	Long-chain Fatty Acid Catabolic Process	Regulation Of Transcription, DNA-templated G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cell-substrate Adhesion Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Stem Cell Population Maintenance Neuron Differentiation T Cell Differentiation In Thymus Substrate Adhesion-dependent Cell Spreading Non-canonical Wnt Signaling Pathway Non-canonical Wnt Signaling Pathway Via JNK Cascade Positive Regulation Of Phosphorylation Negative Regulation Of Ectodermal Cell Fate Specification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of JNK Cascade Somatic Stem Cell Division Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Mesenchymal To Epithelial Transition Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Retinoic Acid Negative Regulation Of Cardiac Muscle Cell Differentiation
Pathways			Class B/2 (Secretin family receptors) PCP/CE pathway PCP/CE pathway Asymmetric localization of PCP proteins WNT5:FZD7-mediated leishmania damping WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Carotid intima media thickness ( 30510157) Daytime sleep phenotypes ( 27126917) Diffusing capacity of carbon monoxide ( 30694715) Pulse pressure ( 27841878 30578418)	Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Blond vs. brown/black hair color ( 30531825) Heel bone mineral density ( 30598549 28869591) Metabolite levels ( 23823483) Risk-taking tendency (4-domain principal component model) ( 30643258) Total body bone mineral density ( 29304378)
Interacting Genes		53 interacting genes: APOD APOL2 AQP6 AQP9 ARL13B ASGR2 BCL2L13 BIK CCR9 CD53 CISD2 CLDN7 CPLX4 CYB5R3 CYBC1 ERGIC3 FAM209A FNDC9 FZD7 GLP1R GOLM1 GPR152 GPR35 GPX8 HIBADH HSD17B13 IER3IP1 KCNJ6 KIR2DL3 LAPTM5 LEUTX LIME1 LMNA LYVE1 MC4R MFF MRM3 PDZK1IP1 PSCA RCHY1 SAR1A SEC22B SLC34A2 SLC7A14 STOM STX1A THAP4 THBD TMEM106C TMEM80 TMX2 VAMP3 VAPB	28 interacting genes: ADCY1 AIG1 AQP9 BCL2L13 CLN8 CLPTM1 DLG1 DLG2 DLG4 FFAR2 GNAS HPCAL1 LEUTX MAGI3 MGST1 NCALD NCS1 PDAP1 PRNP PSME3IP1 SGTA SGTB SLC30A4 SLC35B1 TMEM237 UBQLN1 UBQLN2 UBQLN4
Entrez ID		51390	8324
HPRD ID		16346	04560
Ensembl ID		ENSG00000146416	ENSG00000155760
Uniprot IDs		Q9NVV5	O75084
PDB IDs			4Z33 5T44 5URV 5WBS 6NE2 6NE4 6O3A 6O3B
Enriched GO Terms of Interacting Partners?
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