AIG1 and THBD

Data Source:
BioGRID (two hybrid)

		AIG1	THBD
Description		androgen induced 1	thrombomodulin
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Extracellular Space Vacuolar Membrane Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Apicolateral Plasma Membrane
	Molecular Function	Protein Binding Hydrolase Activity	Transmembrane Signaling Receptor Activity Calcium Ion Binding Protein Binding Signaling Receptor Activity
	Biological Process	Long-chain Fatty Acid Catabolic Process	Female Pregnancy Blood Coagulation Response To X-ray Negative Regulation Of Platelet Activation Negative Regulation Of Blood Coagulation Response To Lipopolysaccharide Leukocyte Migration Response To CAMP Negative Regulation Of Fibrinolysis
Pathways			Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
Drugs			Drotrecogin alfa Ibuprofen Dexibuprofen
Diseases			Inherited thrombophilia
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Carotid intima media thickness ( 30510157) Daytime sleep phenotypes ( 27126917) Diffusing capacity of carbon monoxide ( 30694715) Pulse pressure ( 27841878 30578418)	Blood protein levels in cardiovascular risk ( 28369058) PR interval in Tripanosoma cruzi seropositivity ( 24324551) Venous thromboembolism ( 26888256)
Interacting Genes		53 interacting genes: APOD APOL2 AQP6 AQP9 ARL13B ASGR2 BCL2L13 BIK CCR9 CD53 CISD2 CLDN7 CPLX4 CYB5R3 CYBC1 ERGIC3 FAM209A FNDC9 FZD7 GLP1R GOLM1 GPR152 GPR35 GPX8 HIBADH HSD17B13 IER3IP1 KCNJ6 KIR2DL3 LAPTM5 LEUTX LIME1 LMNA LYVE1 MC4R MFF MRM3 PDZK1IP1 PSCA RCHY1 SAR1A SEC22B SLC34A2 SLC7A14 STOM STX1A THAP4 THBD TMEM106C TMEM80 TMX2 VAMP3 VAPB	31 interacting genes: AIG1 APOC2 APOC4 AQP6 CD79A CIDEB CYBC1 EBP ERGIC3 F2 FAM209A FCER1G GPX8 KIR2DL3 LMNA MMGT1 MTIF3 MUC1 PDZK1IP1 PF4 PHF24 PROC PSENEN RHBDD2 SERPINA5 SLC19A3 SLC35C2 TMEM14B TMEM35A TMEM86B TMX2
Entrez ID		51390	7056
HPRD ID		16346	01764
Ensembl ID		ENSG00000146416	ENSG00000178726
Uniprot IDs		Q9NVV5	P07204
PDB IDs			1ADX 1DQB 1DX5 1EGT 1FGD 1FGE 1HLT 1TMR 1ZAQ 2ADX 3GIS 5TO3
Enriched GO Terms of Interacting Partners?
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