ATRAID and LPP

Data Source:
HPRD (two hybrid)

		ATRAID	LPP
Description		all-trans retinoic acid induced differentiation factor	LIM domain containing preferred translocation partner in lipoma
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Stress Fiber Nucleus Cytosol Plasma Membrane Focal Adhesion
	Molecular Function	Molecular_function Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Bone Mineralization Negative Regulation Of Osteoblast Proliferation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Cellular Protein Catabolic Process	Biological_process Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS			Adult body size ( 32376654) Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184 31361310) Allergic sensitization ( 30013184 23817571) Allergy ( 27182965) Alopecia areata ( 25608926) Asthma ( 31361310 31959851 30929738 27182965 32296059 31619474) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Autoimmune thyroid disease ( 32581359) Autoimmune thyroid diseases (Graves disease or Hashimoto's thyroiditis) ( 22922229) B cell non-Hodgkin lymphoma ( 23749188) B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Basal cell carcinoma ( 31174203 27539887) Blood protein levels ( 29875488) Celiac disease ( 22057235 20190752 30572963 18311140) Chronic kidney disease ( 29124443) Chronic lymphocytic leukemia ( 28165464 26956414) Creatinine levels ( 29124443) Crohn's disease ( 28067908) Cutaneous squamous cell carcinoma ( 27424798) CV-A6-associated hand, foot, and mouth disease (severe vs mild) ( 32634583) Early spontaneous preterm birth ( 31477735) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Estimated glomerular filtration rate ( 29124443) Evening vs. morning chronotype (sMEQ score) ( 32579418) Follicular lymphoma ( 25279986) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 29891935) Glucose homeostasis traits ( 25524916) Granulocyte percentage of myeloid white cells ( 27863252) Graves' disease ( 22922229) Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales) ( 33208821) Hodgkin's lymphoma ( 29196614) IgE levels ( 22075330) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Inflammatory bowel disease ( 28067908) Intraocular pressure ( 29617998 29785010 31959993 29235454) Itch intensity from mosquito bite ( 28199695) Keratinocyte cancer (MTAG) ( 31174203) Mean spheric corpuscular volume ( 32888494) Medication use (adrenergics, inhalants) ( 31015401) Medication use (thyroid preparations) ( 31015401) Monocyte percentage of white cells ( 32888494 27863252) Mortality in sepsis ( 27639821) Mosquito bite size ( 28199695) Multiple sclerosis ( 31604244 24076602) Neutrophil percentage of granulocytes ( 27863252) Nodular sclerosis Hodgkin lymphoma ( 29196614) Obesity-related traits ( 23251661) Platelet distribution width ( 32888494) Renal function-related traits (BUN) ( 22797727) Response to platinum-based chemotherapy (cisplatin) ( 21844884) Self-reported allergy ( 23817569) Serum urea levels ( 30808845) Squamous cell carcinoma ( 31174203) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 27399966) Thyroid stimulating hormone levels ( 32769997) Triglyceride levels ( 32203549) Type 2 diabetes ( 24509480 30054458 30297969 25760438 28869590) Type 2 diabetes (young onset) and obesity ( 24465431) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Vitiligo ( 22951725 20410501 27723757) White matter integrity (bipolar disorder risk interaction) ( 23218918)
Interacting Genes		3 interacting genes: APP LPP MPP1	7 interacting genes: ACTN1 ATP5MF ATRAID MTNR1A SCRIB SHPRH VASP
Entrez ID		51374	4026
HPRD ID		16652	02828
Ensembl ID		ENSG00000138085	ENSG00000145012
Uniprot IDs		Q6UW56	B7Z871 B7Z8W0 B7ZLW0 Q93052
PDB IDs
Enriched GO Terms of Interacting Partners?
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