POMP and KIF1B

Data Source:
BioGRID (two hybrid)

		POMP	KIF1B
Description		proteasome maturation protein	kinesin family member 1B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Nuclear Speck Organelle Membrane	Mitochondrion Kinesin Complex Microtubule Microtubule Associated Complex Synaptic Vesicle Axon Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Axon Cytoplasm
	Molecular Function	Protein Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Kinesin Binding Kinase Binding Scaffold Protein Binding
	Biological Process	Proteasome Assembly	Apoptotic Process Microtubule-based Movement Neuron-neuron Synaptic Transmission Neuromuscular Synaptic Transmission Anterograde Axonal Transport Positive Regulation Of Gene Expression Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport Lysosome Localization Response To Rotenone Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport Cellular Response To Nerve Growth Factor Stimulus Protein Localization To Cell Periphery
Pathways			COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases		Keratosis linearis with ichthyosis congenita and sclerosing keratoderma; KLICK syndrome	Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Breast cancer (menopausal hormone therapy interaction) ( 24080446) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Red blood cell count ( 32888494) Refractive error ( 32231278)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Hand grip strength ( 29691431) Hematocrit ( 27863252) Hepatitis B virus-related hepatocellular carcinoma ( 29246937) Hepatocellular carcinoma ( 20676096) Lateral orbital frontal cortex volume ( 31530798) Mean platelet volume ( 22139419 32888494 27863252) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 18997785) Neutrophil count ( 32888494) Platelet count ( 32888494) Virologic severity in Herpes simplex virus type 2 infection ( 29535370) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) White blood cell count ( 32888494)
Interacting Genes		25 interacting genes: ARMT1 ATXN1 CAPN3 ECT2 FAM107A GPD1 GRB2 KCNA10 KIF1B KLHL41 MPPED2 PSMA1 PSMA3 PSMB1 PSMB10 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PYGM RBM5 SSR4 TTN VCL	22 interacting genes: ARHGAP1 BRCA1 CALM1 CHP1 CLIP4 CPEB1 DLG1 DLG2 DLG3 DLG4 DYSF EEF1A1 GIPC1 LAMTOR5 PATJ PGM1 POMP SIAH1 SNTA1 STARD13 TRIM55 YWHAG
Entrez ID		51371	23095
HPRD ID		12613	05818
Ensembl ID		ENSG00000132963	ENSG00000054523
Uniprot IDs		Q9Y244	O60333
PDB IDs			2EH0
Enriched GO Terms of Interacting Partners?
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