POMP and KLHL41

Data Source:
BioGRID (two hybrid)

		POMP	KLHL41
Description		proteasome maturation protein	kelch like family member 41
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Nuclear Speck Organelle Membrane	Ruffle Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Pseudopodium M Band Cul3-RING Ubiquitin Ligase Complex Sarcoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Proteasome Assembly	Striated Muscle Contraction Protein Ubiquitination Myofibril Assembly Regulation Of Lateral Pseudopodium Assembly Skeletal Muscle Cell Differentiation Post-translational Protein Modification Sarcomere Organization Regulation Of Myoblast Differentiation Skeletal Muscle Fiber Development Regulation Of Myoblast Proliferation Regulation Of Skeletal Muscle Cell Differentiation
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Keratosis linearis with ichthyosis congenita and sclerosing keratoderma; KLICK syndrome
GWAS		Breast cancer (menopausal hormone therapy interaction) ( 24080446) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Red blood cell count ( 32888494) Refractive error ( 32231278)
Interacting Genes		25 interacting genes: ARMT1 ATXN1 CAPN3 ECT2 FAM107A GPD1 GRB2 KCNA10 KIF1B KLHL41 MPPED2 PSMA1 PSMA3 PSMB1 PSMB10 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PYGM RBM5 SSR4 TTN VCL	9 interacting genes: C4orf45 IFRD1 MYBPC1 NRAP POMP RBM4 RCHY1 SLC2A4 TCAP
Entrez ID		51371	10324
HPRD ID		12613	07610
Ensembl ID		ENSG00000132963	ENSG00000239474
Uniprot IDs		Q9Y244	O60662
PDB IDs
Enriched GO Terms of Interacting Partners?
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