PLEKHO1 and RPRD2

Data Source:
BioGRID (affinity chromatography technology)

		PLEKHO1	RPRD2
Description		pleckstrin homology domain containing O1	regulation of nuclear pre-mRNA domain containing 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Ruffle Membrane Muscle Cell Projection Membrane	Nucleoplasm RNA Polymerase II, Holoenzyme
	Molecular Function	Protein Binding	RNA Polymerase II Complex Binding
	Biological Process	Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis	MRNA 3'-end Processing SnRNA Transcription By RNA Polymerase II
Pathways			RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Bitter non-alcoholic beverage consumption ( 31046077) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Broad depression or bipolar disorder ( 30626913) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Neutrophil count ( 32888494) Refractive error ( 32231278) Schizophrenia ( 28991256) Spontaneous coronary artery dissection ( 32887874) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		32 interacting genes: ADAM33 AKT1 AKT2 BNIP2 BRICD5 C10orf88 C4orf3 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB IFI35 LRP10 MMD NAPB PSMC5 RPS20 SMAD5 SMURF1 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1	6 interacting genes: CSNK2A1 MTNR1B PPP1CA PPP1CC SPOP UPF1
Entrez ID		51177	23248
HPRD ID		12217	11084
Ensembl ID		ENSG00000023902	ENSG00000163125
Uniprot IDs		Q53GL0 Q5T4P9	Q5VT52
PDB IDs		3AA1	4FLB
Enriched GO Terms of Interacting Partners?
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