DUOX2 and TXNDC11

Data Source:
HPRD (in vivo)

		DUOX2	TXNDC11
Description		dual oxidase 2	thioredoxin domain containing 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Plasma Membrane Cell Surface Apical Plasma Membrane Cell Junction Cell Leading Edge NADPH Oxidase Complex Apical Part Of Cell Extracellular Exosome	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Peroxidase Activity Calcium Ion Binding Protein Binding NAD(P)H Oxidase H2O2-forming Activity Superoxide-generating NAD(P)H Oxidase Activity Heme Binding	Protein Binding
	Biological Process	Thyroid Hormone Generation Defense Response Response To Oxidative Stress Response To Virus Cytokine-mediated Signaling Pathway Cuticle Development Hormone Biosynthetic Process Superoxide Anion Generation Hydrogen Peroxide Catabolic Process Hydrogen Peroxide Biosynthetic Process Response To CAMP Positive Regulation Of Wound Healing Cellular Oxidant Detoxification Positive Regulation Of Cell Motility
Pathways		Thyroxine biosynthesis
Drugs
Diseases		Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS			Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Plasma renin activity levels ( 29650764) Red cell distribution width ( 32888494) Rheumatoid arthritis ( 30423114 24390342) Triglyceride levels ( 32203549) Weight ( 28552196)
Interacting Genes		1 interacting genes: TXNDC11	21 interacting genes: ACAA1 ATXN7 CDKN1A DUOX1 DUOX2 GFI1B HSP90B1 KLHL38 KRT15 KRT18 MKRN3 NOS3 ORC5 RAB2B RACGAP1 RPS19 RPS6KA5 SOCS3 STAT5A TPO ZNF417
Entrez ID		50506	51061
HPRD ID		05997	07125
Ensembl ID		ENSG00000140279	ENSG00000153066
Uniprot IDs		Q9NRD8	Q6PKC3
PDB IDs
Enriched GO Terms of Interacting Partners?
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