OXTR and YIPF3

Data Source:
BioGRID (two hybrid)

		OXTR	YIPF3
Description		oxytocin receptor	Yip1 domain family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Microvillus Adherens Junction Apical Plasma Membrane	Golgi Apparatus Plasma Membrane Integral Component Of Membrane Transport Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	G Protein-coupled Receptor Activity Oxytocin Receptor Activity Vasopressin Receptor Activity Peptide Hormone Binding Peptide Binding	Protein Binding
	Biological Process	Suckling Behavior Response To Amphetamine Regulation Of Systemic Arterial Blood Pressure By Vasopressin Muscle Contraction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Heart Development Female Pregnancy Lactation Memory Positive Regulation Of Norepinephrine Secretion Telencephalon Development Sleep Positive Regulation Of Synaptic Transmission, GABAergic Response To Estradiol Response To Progesterone Response To Anoxia Response To Cytokine Social Behavior Response To Cocaine Response To Drug Maternal Behavior Sperm Ejaculation Eating Behavior Response To Peptide Hormone Estrous Cycle Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Digestive Tract Development Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Maternal Process Involved In Parturition Positive Regulation Of Penile Erection Negative Regulation Of Gastric Acid Secretion ERK1 And ERK2 Cascade Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Cold-induced Thermogenesis	Cell Differentiation
Pathways		Vasopressin-like receptors G alpha (q) signalling events
Drugs		Oxytocin Carbetocin Atosiban Relcovaptan
Diseases
GWAS		Caudate activity during reward ( 28927378) Chronotype ( 30696823) Depression and alcohol dependence ( 22064162) Liver fibrosis severity in HIV/hepatitis C co-infection ( 27339598) Morning person ( 30696823)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		18 interacting genes: ALAS1 ARRB2 ASH1L AVP CD81 CYFIP2 EMC10 FSCN1 GPRASP1 LCNL1 MVB12A OXT PSMA7 SIRT2 THOC5 TMEM161A TSPAN7 YIPF3	23 interacting genes: CHRM3 CHRM4 DRD2 HOXA1 HRH1 INCA1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP3-2 KRTAP5-9 KRTAP9-4 KRTAP9-8 MC4R NOTCH2NLA OPRM1 OXTR PLSCR1 TRIM42 YIPF4
Entrez ID		5021	25844
HPRD ID		01328	09852
Ensembl ID		ENSG00000180914	ENSG00000137207
Uniprot IDs		B2R9L7 P30559	Q9GZM5
PDB IDs		6TPK
Enriched GO Terms of Interacting Partners?
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