YIPF3 and HRH1

Data Source:
BioGRID (two hybrid)

		YIPF3	HRH1
Description		Yip1 domain family member 3	histamine receptor H1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Integral Component Of Membrane Transport Vesicle Intracellular Membrane-bounded Organelle	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Dendrite Synapse
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Neurotransmitter Receptor Activity
	Biological Process	Cell Differentiation	Inflammatory Response G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Chemical Synaptic Transmission Memory Visual Learning Positive Regulation Of Inositol Trisphosphate Biosynthetic Process Regulation Of Vascular Permeability Positive Regulation Of Vasoconstriction Inositol Phosphate-mediated Signaling Regulation Of Synaptic Plasticity Eosinophil Chemotaxis Cellular Response To Histamine G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways			Histamine receptors G alpha (q) signalling events
Drugs			Citalopram Benzatropine Ziprasidone Clemastine Amitriptyline Olanzapine Cetirizine Terfenadine Buclizine Clozapine Doxylamine Mirtazapine Dexbrompheniramine Loxapine Promazine Triprolidine Prochlorperazine Cyproheptadine Loratadine Imipramine Chlorpromazine Haloperidol Nortriptyline Amoxapine Lamotrigine Hydroxyzine Cinnarizine Astemizole Trazodone Paroxetine Azatadine Trimipramine Risperidone Meclizine Carbinoxamine Epinastine Benzquinamide Olopatadine Propiomazine Tripelennamine Tolazoline Brompheniramine Methdilazine Ketotifen Maprotiline Fexofenadine Desloratadine Azelastine Dimenhydrinate Promethazine Mequitazine Diphenhydramine Emedastine Levocabastine Chlorpheniramine Doxepin Diphenylpyraline Desipramine Orphenadrine Escitalopram Cyclizine Quetiapine Bromodiphenhydramine Aripiprazole Chlorprothixene Alimemazine Paliperidone Methotrimeprazine Aceprometazine Phenindamine Pheniramine Zuclopenthixol Clofedanol Flunarizine Bepotastine Tesmilifene Iloperidone HY10275 OBE101 SO-101 Histamine Epicept NP-1 Cariprazine Mianserin Pizotifen Asenapine Ocaperidone Levocetirizine Esmirtazapine Mepyramine Betahistine Alcaftadine Antazoline Chloropyramine Dimetindene Isothipendyl Perospirone Chlorcyclizine Butriptyline Dosulepin Lorpiprazole Acrivastine Dexchlorpheniramine maleate Thonzylamine Bilastine Rupatadine Aripiprazole lauroxil
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Male-pattern baldness ( 28196072) Mortality in sepsis ( 27639821) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 27618447 27618452)
Interacting Genes		23 interacting genes: CHRM3 CHRM4 DRD2 HOXA1 HRH1 INCA1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP3-2 KRTAP5-9 KRTAP9-4 KRTAP9-8 MC4R NOTCH2NLA OPRM1 OXTR PLSCR1 TRIM42 YIPF4	11 interacting genes: ADGRA3 ATP6V0A1 CD81 CNBP DHRS7 LIMS2 MAT2B SLC35B1 SLC43A2 WLS YIPF3
Entrez ID		25844	3269
HPRD ID		09852	02544
Ensembl ID		ENSG00000137207	ENSG00000196639
Uniprot IDs		Q9GZM5	P35367
PDB IDs			3RZE
Enriched GO Terms of Interacting Partners?
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