ORM1 and BLVRB

Data Source:
BioGRID (two hybrid)

		ORM1	BLVRB
Description		orosomucoid 1	biliverdin reductase B
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Tertiary Granule Lumen	Nucleoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding	Biliverdin Reductase (NAD(P)+) Activity Protein Binding Riboflavin Reductase (NADPH) Activity Biliberdin Reductase NAD+ Activity Biliverdin Reductase (NADP+) Activity
	Biological Process	Platelet Degranulation Regulation Of Immune System Process Acute-phase Response Inflammatory Response Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production Neutrophil Degranulation	Heme Catabolic Process
Pathways		Platelet degranulation Neutrophil degranulation	Heme degradation
Drugs		Amsacrine Lidocaine Progesterone Chlorpromazine Dipyridamole Thalidomide	Riboflavin NADH Biliverdine IX Alpha Flavin mononucleotide Nicotinamide adenine dinucleotide phosphate Lumichrome Mesobiliverdin IV alpha
Diseases
GWAS		End-stage coagulation ( 23381943) Thrombin generation potential phenotypes ( 24357727) Tourette syndrome ( 22889924)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		9 interacting genes: ALB BLVRB CCR5 GLUD1 GSDMB PIK3R3 SERPINE1 TMEM37 TP63	4 interacting genes: ANXA10 HMOX1 ORM1 RPL31
Entrez ID		5004	645
HPRD ID		00724	02967
Ensembl ID		ENSG00000229314	ENSG00000090013
Uniprot IDs		P02763	P30043 V9HWI1
PDB IDs		3KQ0	1HDO 1HE2 1HE3 1HE4 1HE5 5OOG 5OOH 6OPL
Enriched GO Terms of Interacting Partners?
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