ORM1 and TMEM37

Data Source:
BioGRID (two hybrid)

		ORM1	TMEM37
Description		orosomucoid 1	transmembrane protein 37
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Tertiary Granule Lumen	Integral Component Of Membrane
	Molecular Function	Protein Binding	Voltage-gated Ion Channel Activity Calcium Channel Activity
	Biological Process	Platelet Degranulation Regulation Of Immune System Process Acute-phase Response Inflammatory Response Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production Neutrophil Degranulation	Regulation Of Ion Transmembrane Transport Calcium Ion Transmembrane Transport
Pathways		Platelet degranulation Neutrophil degranulation
Drugs		Amsacrine Lidocaine Progesterone Chlorpromazine Dipyridamole Thalidomide
Diseases
GWAS		End-stage coagulation ( 23381943) Thrombin generation potential phenotypes ( 24357727) Tourette syndrome ( 22889924)
Interacting Genes		9 interacting genes: ALB BLVRB CCR5 GLUD1 GSDMB PIK3R3 SERPINE1 TMEM37 TP63	6 interacting genes: HBP1 MPP3 ORM1 PLA2G12A SPIB UBQLN1
Entrez ID		5004	140738
HPRD ID		00724	15536
Ensembl ID		ENSG00000229314	ENSG00000171227
Uniprot IDs		P02763	E7EMC0 Q86SV2 Q8WXS4
PDB IDs		3KQ0
Enriched GO Terms of Interacting Partners?
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