NVL and CRMP1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NVL	CRMP1
Description		nuclear VCP like	collapsin response mediator protein 1
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GO Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Nucleus Nucleoplasm Telomerase Holoenzyme Complex Nucleolus Membrane	Nucleus Centrosome Spindle Cytosol Growth Cone Midbody Perikaryon
	Molecular Function	RNA Binding Protein Binding ATP Binding ATPase Activity Preribosome Binding	Dihydropyrimidinase Activity Protein Binding Filamin Binding Identical Protein Binding
	Biological Process	RRNA Processing Positive Regulation Of Protein Binding Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Positive Regulation Of Telomerase Activity Regulation Of Protein Localization To Nucleolus	Microtubule Cytoskeleton Organization Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance Negative Regulation Of Neuron Projection Development Negative Regulation Of Actin Filament Binding
Pathways			CRMPs in Sema3A signaling
Drugs
Diseases
GWAS		Major depressive disorder ( 21042317) Mean corpuscular hemoglobin ( 32888494)	Blood trace element (Zn levels) ( 23720494) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		9 interacting genes: CRMP1 FBXO7 HSPB1 LINC00839 OSGEP RNF4 RPL5 TTF2 UBE2I	80 interacting genes: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DPYSL3 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LRRK2 LSM2 MAP3K20 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RACK1 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1 ZNF24
Entrez ID		4931	1400
HPRD ID		03887	03913
Ensembl ID		ENSG00000143748	ENSG00000072832
Uniprot IDs		B4DF43 O15381	B3KT07 B3KV96 E9PD68 Q14194 Q96I11 X5DNI1
PDB IDs		2X8A 6RO1	4B3Z
Enriched GO Terms of Interacting Partners?
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