NTRK3 and PLCG1

  • Data Source:
  • BioGRID (pull down)
  • HPRD (in vitro, in vivo)

NTRK3

PLCG1

Description neurotrophic receptor tyrosine kinase 3 phospholipase C gamma 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blood protein levels ( 30072576)
  • Diabetic peripheral neuropathy in type 2 diabetes ( 31127053)
  • Gaucher disease severity ( 22388998)
  • General risk tolerance (MTAG) ( 30643258)
Interacting Genes 28 interacting genes: APP BEX3 DOK5 DOK6 DYNLL1 ERBB2 FRS2 HEY1 HTR2A IRAK1 IRAK3 JUN KIDINS220 KPNA4 MAPK1 MAPK3 NELFB NGFR NSD1 NTF3 PLCG1 PTPN1 RASGRF1 SHC1 SHC2 SORT1 SQSTM1 WDR13 111 interacting genes: ABL1 AGAP2 AGTR1 AKT1 ALK AR ARHGAP32 ARHGEF5 AXL BAG3 BCR BLNK BTK CBL CD22 CD28 CTSS DAB1 DAPP1 DDR1 DGKZ DNM1 DOK1 EEF1A1 EGFR EPHB2 EPOR ERBB2 ERBB3 ERBB4 FGFR1 FGFR2 FGFR4 FLT1 FYN GAB1 GAB2 GHR GIT1 GRAP GRB2 GRIN1 GRIN2A GRIN2B GSN GTF2H1 HCK INPP5D INSR IRS2 ITK KDR KHDRBS1 KIT LAT LAT2 LCK LCP2 LIFR LYN MAPT MET MST1R NCAM1 NCK1 NPM1 NTRK1 NTRK2 NTRK3 PAK1 PDGFRA PDGFRB PECAM1 PICALM PITPNA PKN2 PLD2 PRKD1 PRMT8 PTK2 PTPN11 PTPRJ RACK1 RET RHOA RHOU SELE SH2D2A SH3BP2 SHB SHC1 SNAP91 SOCS7 SOS1 SOS2 SRC SYK SYN1 SYNCRIP TEC TNK1 TRIM14 TRPC3 TRPM7 TUB USO1 VAV1 VAV3 VIL1 WAS ZAP70
Entrez ID 4916 5335
HPRD ID 01870 01398
Ensembl ID ENSG00000140538 ENSG00000124181
Uniprot IDs B7Z7U4 O95193 Q16288 Q96CY4 X5D2R1 X5D7M5 X5DNW6 P19174 Q4LE43 Q9UFY1
PDB IDs 1WWC 3V5Q 4YMJ 6KZC 6KZD 1HSQ 2HSP 4EY0 4FBN
Enriched GO Terms of Interacting Partners?
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