ATP2B2 and PDZD11

Data Source:
HPRD (two hybrid, in vitro)

		ATP2B2	PDZD11
Description		ATPase plasma membrane Ca2+ transporting 2	PDZ domain containing 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome Presynapse Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse	Extracellular Region Cytosol Cell-cell Junction Adherens Junction Basolateral Plasma Membrane Synapse Pore Complex Presynapse
	Molecular Function	Calcium Transmembrane Transporter Activity, Phosphorylative Mechanism Protein Binding Calmodulin Binding ATP Binding ATPase-coupled Cation Transmembrane Transporter Activity PDZ Domain Binding Metal Ion Binding Calcium-transporting ATPase Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Calcium-transporting ATPase Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration	Protein Binding
	Biological Process	Calcium Ion Transport Cellular Calcium Ion Homeostasis Sensory Perception Of Sound Neuron Differentiation Ion Transmembrane Transport Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Regulation Of Cardiac Conduction	Biotin Metabolic Process Neurotransmitter Secretion Pantothenate Metabolic Process Antimicrobial Humoral Response Ion Transmembrane Transport Maintenance Of Epithelial Cell Apical/basal Polarity Pore Complex Assembly Transmembrane Transport Protein Localization To Basolateral Plasma Membrane
Pathways		Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases	Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases
Drugs		Halothane Desflurane
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Cognitive decline rate in late mild cognitive impairment ( 26252872) Manganese levels ( 26025379) Metabolite levels ( 19043545)
Interacting Genes		8 interacting genes: DLG1 DLG2 DLG4 ERBIN PDZD11 PRKCA SLC9A3R2 SNTA1	5 interacting genes: ATP2B2 ATP7A MAGI2 PLEKHA5 SIGMAR1
Entrez ID		491	51248
HPRD ID		00160	06622
Ensembl ID		ENSG00000157087	ENSG00000120509
Uniprot IDs		A0A024R2E4 Q01814 Q4LE63	Q5EBL8
PDB IDs
Enriched GO Terms of Interacting Partners?
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