MYBPC1 and ASH2L

Data Source:
BioGRID (two hybrid)

		MYBPC1	ASH2L
Description		myosin binding protein C1	ASH2 like, histone lysine methyltransferase complex subunit
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GO Annotations	Cellular Component	Cytosol Myofibril Myosin Filament	Nucleus Nucleoplasm Histone Methyltransferase Complex MLL3/4 Complex Set1C/COMPASS Complex
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle Myosin Binding Titin Binding	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Beta-catenin Binding Histone Methyltransferase Activity (H3-K4 Specific) Metal Ion Binding
	Biological Process	Cell Adhesion Muscle Filament Sliding	Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Population Proliferation Hemopoiesis Response To Estrogen Regulation Of Megakaryocyte Differentiation Histone H3-K4 Methylation Beta-catenin-TCF Complex Assembly
Pathways		Striated Muscle Contraction	Formation of the beta-catenin:TCF transactivating complex PKMTs methylate histone lysines Deactivation of the beta-catenin transactivating complex Activation of anterior HOX genes in hindbrain development during early embryogenesis RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Lung function (FEV1) ( 24023788) Memory decline ( 31985465)	Menopause (age at onset) ( 22267201) Schizophrenia ( 29483656)
Interacting Genes		23 interacting genes: ACO1 AMOT ANKRD1 ASH2L C1QTNF9 CALM1 CAPN3 CLIP4 DNAJB5 DNAJB6 DYSF FHL1 FHL2 FHL3 KLHL41 MEOX2 MYBPC2 NCF1 RAF1 SGCG TRIM55 TRIM63 TTN	37 interacting genes: ACTC1 ACTN2 ANKRD1 BARD1 BRCA1 CCNC CEP76 CHD8 COPS6 CTNNB1 DNMT3L DPY30 EP300 H3-4 H3C1 KMT2A KMT2B KMT2D KMT2E MEN1 MESD MKRN1 MYBPC1 MYOM3 PPP1CC PRMT1 RBBP5 SMAD9 SMURF1 SMURF2 TGFBR1 TP53 TTN UNC119 WDR5 WWP1 ZSCAN1
Entrez ID		4604	9070
HPRD ID		01185	05309
Ensembl ID		ENSG00000196091	ENSG00000129691
Uniprot IDs		A8KAB1 B3KPP3 Q00872 Q86TA8	B4DPT1 F5H8F7 Q9UBL3
PDB IDs		1X44 2DAV 2YUV 2YUW 2YUX 2YUZ 2YXM	3RSN 3S32 3TOJ 4RIQ 4X8N 4X8P 5F6K 5F6L 6E2H 6KIU 6KIV 6KIW 6KIX 6KIZ 6PWV 7BRE
Enriched GO Terms of Interacting Partners?
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