MYB and SMARCA2

MYB

SMARCA2

Description MYB proto-oncogene, transcription factor SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701)
  • Asthma (childhood onset) ( 27611488)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Brain morphology (MOSTest) ( 32665545)
  • Lead levels ( 26025379)
  • Lung function (FEV1) ( 30061609)
  • Lung function (FVC) ( 30061609)
  • Monobrow ( 27182965)
  • Neuritic plaque ( 31497858)
  • Nose size ( 27182965)
  • Parkinson's disease ( 26227905)
  • Superior frontal gyrus grey matter volume ( 25335168)
  • Systolic blood pressure ( 26969751)
  • Thyroid volume in Hashimoto’s thyroiditis ( 32019955)
Interacting Genes 49 interacting genes: BTRC CCND3 CEBPB CEBPE CHD3 CNOT9 CREBBP CSNK2A1 EP300 ERC2 FBXW2 FBXW5 FBXW7 H2AC4 H2BC3 H3-4 H3C1 H4C1 HIPK2 HLF KAT2A MAF MAPK1 MYBBP1A MYOZ2 NCL NCOR1 NLK PAIP1 PAX5 PIAS1 PML PPM1K RBX1 RPL4 SIN3A SKI SKP2 SMARCA2 SND1 SP100 SUMO1 SUMO2 TRIM28 TTF2 UBE2I UPF2 ZFHX3 ZMYND11 27 interacting genes: ACTL6A ACTL6B AR ARID1B BEND7 BRCA1 CEBPA ESR1 H3C1 HSPB1 KHDRBS1 MDM2 MDM4 MECP2 MYB MYC NR0B2 NR3C1 NR4A2 PHB PITX1 PRMT5 PRPF6 RAP1A SDCBP SIN3B SS18
Entrez ID 4602 6595
HPRD ID 01810 02483
Ensembl ID ENSG00000118513 ENSG00000080503
Uniprot IDs P10242 Q708E9 B1ALF6 B4DNT1 B4DSC8 F6T8Q0 F6VDE0 P51531 Q56A76 Q8N9Q1
PDB IDs 2DAT 4QY4 5DKC 5DKH 6EG2 6EG3 6HAX 6HAY 6HAZ
Enriched GO Terms of Interacting Partners?
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