MAP1LC3C and LMNB1

Data Source:
BioGRID (pull down)

		MAP1LC3C	LMNB1
Description		microtubule associated protein 1 light chain 3 gamma	lamin B1
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GO Annotations	Cellular Component	Autophagosome Membrane Autophagosome Cytosol Microtubule Endomembrane System Organelle Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule	Nucleus Nuclear Envelope Nuclear Inner Membrane Lamin Filament Nucleoplasm Membrane Nuclear Matrix Nuclear Membrane
	Molecular Function	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding	Structural Molecule Activity Protein Binding Phospholipase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Protein Exit From Endoplasmic Reticulum Aggrephagy Autophagosome Maturation	Interleukin-12-mediated Signaling Pathway
Pathways		Macroautophagy	Meiotic synapsis Formation of Senescence-Associated Heterochromatin Foci (SAHF) Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Breakdown of the nuclear lamina Depolymerisation of the Nuclear Lamina Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 28552196) Metabolite levels ( 23823483)	Blood protein levels ( 30072576 29875488) Body fat percentage ( 31752434) Parkinson's disease (motor and cognition) ( 22658654)
Interacting Genes		32 interacting genes: AMBRA1 ANK2 ANK3 ATG13 ATG4B ATXN3 CALCOCO2 CAPN3 CUL3 GMEB2 IRGM KBTBD6 KBTBD7 LAT LMNB1 MEFV MISP NEDD4 OPRM1 OPTN RHOXF1 RUFY4 TAX1BP1 TBC1D25 TNIP1 TP53INP1 TRIM21 TRIM32 TSR2 WDFY3 WDR81 ZNF24	44 interacting genes: ABCG8 ATF4 CASP3 CASP6 CCDC88B CDK1 CENPH DMAP1 FAM169A GABARAP GIT2 GZMA GZMB KPNA1 KPNA5 KPNA6 LBR LMNA LMNB2 M1AP MAP1LC3A MAP1LC3C MBIP MELK PIAS2 PIH1D2 PLEC PPP1R13B PRKCA PRKCB PRKCD PRPH PTEN RNF123 SERPINA3 SNAPIN SRPK2 SUMO4 TMPO TOR1AIP1 TP53BP2 UBE2I URB2 YWHAQ
Entrez ID		440738	4001
HPRD ID		14226	01036
Ensembl ID		ENSG00000197769	ENSG00000113368
Uniprot IDs		Q9BXW4	B4DZT3 P20700
PDB IDs		2NCN 3VVW 3WAM 3WAP 5DPW	2KPW 3JT0 3TYY 3UMN 5VVX
Enriched GO Terms of Interacting Partners?
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