MZT1 and TRIM72

Data Source:
BioGRID (two hybrid)

		MZT1	TRIM72
Description		mitotic spindle organizing protein 1	tripartite motif containing 72
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GO Annotations	Cellular Component	Centrosome Spindle Cytosol Gamma-tubulin Ring Complex Interphase Microtubule Organizing Center	Cytoplasm Cytoplasmic Vesicle Membrane Sarcolemma
	Molecular Function	Protein Binding	Phosphatidylserine Binding Protein Binding Zinc Ion Binding Ubiquitin Conjugating Enzyme Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Gamma-tubulin Complex Localization Microtubule Nucleation By Interphase Microtubule Organizing Center Mitotic Spindle Assembly	Plasma Membrane Repair Muscle System Process Exocytosis Muscle Contraction Muscle Organ Development Negative Regulation Of Myotube Differentiation Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Insulin Receptor Signaling Pathway Protein Homooligomerization
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	Smooth Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases
GWAS		Chronotype ( 30696823) Obsessive-compulsive disorder ( 22889921)
Interacting Genes		4 interacting genes: CINP CYGB REPS1 TRIM72	18 interacting genes: ABI2 C1orf216 INSR IRS1 MED21 MZT1 NMI PPP3CA SMARCD1 TCF12 TRIM32 UBE2C UBE2D3 UBE2H UBE2I UBE2N VSIG4 ZNF655
Entrez ID		440145	493829
HPRD ID		19041	17412
Ensembl ID		ENSG00000204899	ENSG00000177238
Uniprot IDs		Q08AG7	Q6ZMU5
PDB IDs		6L81 6X0U	3KB5
Enriched GO Terms of Interacting Partners?
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