MOBP and WAC

Data Source:
BioGRID (two hybrid)

		MOBP	WAC
Description		myelin associated oligodendrocyte basic protein	WW domain containing adaptor with coiled-coil
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cortical Actin Cytoskeleton Myelin Sheath Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Actin Binding Protein Binding Myosin Binding Structural Constituent Of Myelin Sheath	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding
	Biological Process	Nervous System Development Central Nervous System Myelin Formation	Cellular Response To DNA Damage Stimulus Histone Monoubiquitination Positive Regulation Of Macroautophagy Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Positive Regulation Of Transcription, DNA-templated Histone H2B Conserved C-terminal Lysine Ubiquitination
Pathways		Transcriptional Regulation by MECP2	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Amyotrophic lateral sclerosis ( 27455348) Amyotrophic lateral sclerosis (sporadic) ( 28931804) Attention deficit hyperactivity disorder ( 18839057) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive performance ( 19734545) Cortical surface area (MOSTest) ( 32665545) Corticobasal degeneration ( 26077951) Dentate gyrus volume x schizophrenia interaction ( 31155012) Progressive supranuclear palsy ( 30089514 21685912) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Diastolic blood pressure ( 30224653) Intraocular pressure ( 29617998) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Multiple myeloma ( 27363682)
Interacting Genes		21 interacting genes: APP BOLA2 BOLA2B KRT40 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 MEOX2 SDCBP TRIM41 WAC ZNF23	25 interacting genes: AKAP9 APP CCDC6 CDC37 CRKL DYDC1 HMG20B KLC3 KRT15 LNX1 MOBP MTUS2 NDE1 NFE2L2 POLR2A SYTL5 TFIP11 TNS2 TRAF1 TRAF3IP1 TRAF3IP3 UBQLN4 VCP VCPIP1 ZDHHC17
Entrez ID		4336	51322
HPRD ID		02973	18291
Ensembl ID		ENSG00000168314	ENSG00000095787
Uniprot IDs		A0A0S2Z3W1 Q13875	Q9BTA9
PDB IDs
Enriched GO Terms of Interacting Partners?
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