WAC and HMG20B

Data Source:
BioGRID (two hybrid)

		WAC	HMG20B
Description		WW domain containing adaptor with coiled-coil	high mobility group 20B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Nucleus Nucleoplasm Chromosome Nuclear Body
	Molecular Function	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding	DNA Binding Protein Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Histone Monoubiquitination Positive Regulation Of Macroautophagy Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Positive Regulation Of Transcription, DNA-templated Histone H2B Conserved C-terminal Lysine Ubiquitination	Chromatin Organization Cell Cycle Blood Coagulation Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation
Pathways		E3 ubiquitin ligases ubiquitinate target proteins	HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Intraocular pressure ( 29617998) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Multiple myeloma ( 27363682)
Interacting Genes		25 interacting genes: AKAP9 APP CCDC6 CDC37 CRKL DYDC1 HMG20B KLC3 KRT15 LNX1 MOBP MTUS2 NDE1 NFE2L2 POLR2A SYTL5 TFIP11 TNS2 TRAF1 TRAF3IP1 TRAF3IP3 UBQLN4 VCP VCPIP1 ZDHHC17	28 interacting genes: APP BRCA2 C14orf119 CCDC102B CCDC136 CCDC85B E2F6 ERP29 FBXO7 HMG20A HNRNPL KIF4A KRT15 KRT38 MID1 NKX3-1 NUTF2 PHF21A PIAS2 PPP1R13B SNAPC5 SYCE1 TACC2 TFIP11 TRAF1 USHBP1 VIM WAC
Entrez ID		51322	10362
HPRD ID		18291	05703
Ensembl ID		ENSG00000095787	ENSG00000064961
Uniprot IDs		Q9BTA9	Q9P0W2
PDB IDs
Enriched GO Terms of Interacting Partners?
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