LHX8 and FOSL2

  • Data Source:
  • BioGRID (two hybrid)

LHX8

FOSL2

Description LIM homeobox 8 FOS like 2, AP-1 transcription factor subunit
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359)
  • Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359)
  • Allergic disease (asthma, hay fever or eczema) ( 29679657)
  • Allergic rhinitis ( 30013184)
  • Blond vs. brown/black hair color ( 30531825)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 28067908 23128233)
  • Soluble interleukin-2 receptor subunit alpha ( 26293465)
  • Systolic blood pressure ( 28135244 30578418)
  • Triglyceride levels ( 32203549)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Type 1 diabetes ( 21980299)
Interacting Genes 27 interacting genes: ABI2 ATF2 ATF6B AXIN1 BANP CCHCR1 CRK CSNK2A1 EFS FIGLA FOSL2 FOXN1 GINS4 KLF3 KRT85 LDB1 LDB2 NEDD9 NUTM1 PLCG2 PRPF31 SCYL3 SIK1B SUV39H1 TBC1D1 TBC1D22B ZBTB24 22 interacting genes: ATF2 BACH2 CREB5 CYTH1 DDIT3 DNAJA3 DNMT3L EP300 FHL3 GMCL1 GOPC JUN JUNB JUND LHX8 LRIF1 LUZP4 MEOX2 NME7 POLR2G SRA1 TRAF1
Entrez ID 431707 2355
HPRD ID 17275 03343
Ensembl ID ENSG00000162624 ENSG00000075426
Uniprot IDs Q68G74 P15408 Q9H5M2
PDB IDs
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?