FOSL2 and NME7

Data Source:
BioGRID (two hybrid)

		FOSL2	NME7
Description		FOS like 2, AP-1 transcription factor subunit	NME/NM23 family member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Centrosome Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Keratinocyte Development Regulation Of Transcription By RNA Polymerase II Cell Death Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Fibroblast Proliferation	Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process
Pathways			Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29679657) Allergic rhinitis ( 30013184) Blond vs. brown/black hair color ( 30531825) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Soluble interleukin-2 receptor subunit alpha ( 26293465) Systolic blood pressure ( 28135244 30578418) Triglyceride levels ( 32203549) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Type 1 diabetes ( 21980299)	Coronary artery disease ( 29212778) D-dimer levels ( 21502573) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Left-handedness ( 32989287) Pulse pressure ( 27841878 30578418) QT interval ( 30679814) Systolic blood pressure ( 27841878 30578418) Venous thromboembolism ( 21980494 22672568)
Interacting Genes		22 interacting genes: ATF2 BACH2 CREB5 CYTH1 DDIT3 DNAJA3 DNMT3L EP300 FHL3 GMCL1 GOPC JUN JUNB JUND LHX8 LRIF1 LUZP4 MEOX2 NME7 POLR2G SRA1 TRAF1	75 interacting genes: AMOTL2 ARHGAP9 BTBD6 C1orf189 CARD10 CBY2 CCDC136 CCDC33 CCDC88B CCHCR1 CDC42EP2 CEP72 DDIT4L DDX1 DISC1 DNAI7 EFHC2 FKBP6 FLOT1 FOSL1 FOSL2 GATAD2B GLIS2 GOLGA2 GSC2 HAUS8 IKZF1 IKZF3 INCA1 ISY1-RAB43 KRT18 KRT75 LNX1 MAP4K4 MED11 MED30 MEI4 MEOX2 MYOT NAB2 NEFL NFKBIL1 NIF3L1 NME4 NT5C2 OFD1 PAX4 PIAS2 PICK1 POU6F2 PROSER3 PSMA1 REL RUBCN SHTN1 SNAPIN SNX32 SYCE1 TCF4 TCHP TEKT1 TEPSIN THAP10 TNIP1 TNNI2 TRIM27 TRIM48 TUFT1 YWHAQ ZBTB48 ZNF23 ZNF263 ZNF343 ZNF526 ZNF620
Entrez ID		2355	29922
HPRD ID		03343	11394
Ensembl ID		ENSG00000075426	ENSG00000143156
Uniprot IDs		P15408 Q9H5M2	A0A024R8Z7 Q9Y5B8
PDB IDs
Enriched GO Terms of Interacting Partners?
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