MLH1 and FRMD6

  • Data Source:
  • BioGRID (two hybrid, two hybrid, two hybrid)
  • HPRD (two hybrid)

MLH1

FRMD6

Description mutL homolog 1 FERM domain containing 6
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Platelet distribution width ( 32888494)
  • Schizophrenia ( 28991256)
  • Subjective response to lithium treatment ( 26503763)
  • Anticoagulant levels ( 22216198)
  • Brain structure ( 20171287)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
  • Hippocampal atrophy ( 19668339)
  • Lung cancer (smoking interaction) ( 24658283)
  • Multiple sclerosis ( 31604244)
  • Nonsyndromic cleft lip with or without cleft palate ( 28087736)
  • Total ventricular volume ( 21116278)
  • Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes 139 interacting genes: ABCC3 ABHD16A ACER3 ACTG2 AGR2 AIFM1 ALDOA ALDOB ANXA6 AP1B1 AP2B1 APRT ARAF ASS1 ATF2 BAAT BLM BRCA1 BTBD2 C9orf152 CAB39L CAPN5 CASP3 CBY2 CCDC180 CCDC33 CCDC74B CDCA7L CDKL5 CEP126 CEP76 CKAP4 CKB CTSV CYLC2 DDX47 EEF1G EEF2 EIF2A ELP6 ENKD1 EXO1 EXOC3 FAM228A FAM50B FAM90A1 FAN1 FBXO32 FCGBP FLNB FRAT2 FRMD6 GABARAP GSTP1 HDAC6 IGKC ISY1 KPNA2 KPNA5 KPRP LEF1 LGALS4 LUC7L3 LY96 MAGEA8 MAP2K6 MBD3L1 MBD4 MLH3 MORN3 MPG MSH3 MSH4 MUC2 MYC MYL6 MYOG NANOS3 NDRG1 NELFA NFIX NME4 NT5C3B ORC4 PARP12 PARVA PCNA PER2 PIP4K2B PMS1 PMS2 PPP1R13B PPP2CB PRR5L PSMA1 PTGDS PTPN3 PTPRH RAD23B RAD9A RADX RAPGEFL1 RBM48 RSPH3 SEC61A1 SELENBP1 SERPINF1 SMAD1 SPATA8 SQSTM1 STAP2 STX17 SYF2 TASOR2 TDRD7 TFAP2D TLE5 TRIM23 TRIM29 TRMO TSGA13 TXN TXN2 U2AF1 U2AF1L5 UBOX5 VAMP8 XPA ZBED1 ZC3H11A ZER1 ZFP57 ZFP90 ZMAT5 ZNF177 ZNF212 ZNF474 ZNF559-ZNF177 ZNF774 27 interacting genes: - BLZF1 COX6B2 DNAJA3 EXOC5 GMCL1 HMBOX1 IKZF1 JMJD6 LZTS2 MAK16 MED4 MID2 MLH1 NKAPD1 PARD6B RASSF8 SSX2IP SUV39H1 SYT17 TCF12 TLK2 TRIM55 TRIM63 TSC22D4 WDR7 YWHAB
Entrez ID 4292 122786
HPRD ID 00390 12646
Ensembl ID ENSG00000076242 ENSG00000139926
Uniprot IDs A0A024R2S9 P40692 Q59EG3 Q96NE9
PDB IDs 3RBN 4P7A 5U5P
Enriched GO Terms of Interacting Partners?
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