MKI67 and NIFK

		MKI67	NIFK
Description		marker of proliferation Ki-67	nucleolar protein interacting with the FHA domain of MKI67
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GO Annotations	Cellular Component	Condensed Chromosome Nucleus Nucleoplasm Chromosome Nucleolus Membrane Nuclear Body	Condensed Nuclear Chromosome Nucleoplasm Chromosome Nucleolus Cytoplasm
	Molecular Function	DNA Binding RNA Binding Protein Binding ATP Binding Protein C-terminus Binding	RNA Binding Protein Binding
	Biological Process	Cell Cycle Regulation Of Mitotic Nuclear Division Cell Population Proliferation Regulation Of Chromosome Segregation Regulation Of Chromatin Organization	Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Transcription RRNA Metabolic Process Protein-containing Complex Assembly
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Drug experimentation measurement ( 30718321) Lead levels ( 26025379) Select biomarker traits ( 17903293) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		14 interacting genes: CBX3 CBX5 CDK1 ECPAS HINFP KIF15 NIFK PRKCB PTEN SMN1 SUMO2 TK1 TRIM55 TRIM63	3 interacting genes: MKI67 TNIP1 ZDHHC17
Entrez ID		4288	84365
HPRD ID		08902	17576
Ensembl ID		ENSG00000148773	ENSG00000155438
Uniprot IDs		P46013	Q9BYG3
PDB IDs		1R21 2AFF 5J28	2AFF
Enriched GO Terms of Interacting Partners?
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