MEF2D and CABIN1

Data Source:
HPRD (in vivo)

		MEF2D	CABIN1
Description		myocyte enhancer factor 2D	calcineurin binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytosol Aggresome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Activating Transcription Factor Binding Protein Homodimerization Activity Histone Deacetylase Binding Protein Heterodimerization Activity Sequence-specific Double-stranded DNA Binding	Protein Phosphatase Inhibitor Activity Nucleosome Binding
	Biological Process	Osteoblast Differentiation Endochondral Ossification Chondrocyte Differentiation Regulation Of Transcription By RNA Polymerase II Apoptotic Process Nervous System Development Adult Heart Development Muscle Organ Development Cell Differentiation Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation	DNA Replication-independent Nucleosome Assembly Cell Surface Receptor Signaling Pathway Negative Regulation Of Phosphoprotein Phosphatase Activity
Pathways		Transcriptional activation of mitochondrial biogenesis Circadian Clock Myogenesis NGF-stimulated transcription NGF-stimulated transcription	Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Headache ( 29397368) Medication use (antimigraine preparations) ( 31015401) Migraine ( 22683712 27182965 23793025 27322543) Migraine - clinic-based ( 23793025) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) TPE interval (resting) ( 32386560) White blood cell count ( 32888494)	Acne (severe) ( 24927181) Amyotrophic lateral sclerosis ( 23624525) Coronary artery disease ( 29212778) S-phenylmercapturic acid levels in smokers ( 26959369) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		24 interacting genes: - APP ASCL1 CABIN1 CARM1 CASP7 CDK6 COPS5 DNMT3L EP300 FBXO7 HDAC4 HDAC5 MAPK14 MAPK7 MEF2A MEF2C NFATC2 PRKACA PRMT5 SKP2 SNCA SP1 YWHAQ	12 interacting genes: AMPH BORCS8-MEF2B CALM1 CAMK4 DNM1 GRM1 MEF2B MEF2D PPP3CA PPP3CB PPP3CC YWHAQ
Entrez ID		4209	23523
HPRD ID		02810	10369
Ensembl ID		ENSG00000116604	ENSG00000099991
Uniprot IDs		Q14814	A0A024R1E5 A0A087WWW8 Q9Y6J0
PDB IDs			1N6J
Enriched GO Terms of Interacting Partners?
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