MCC and IMP3

Data Source:
BioGRID (two hybrid)

		MCC	IMP3
Description		MCC regulator of WNT signaling pathway	IMP U3 small nucleolar ribonucleoprotein 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Cytoplasmic Ribonucleoprotein Granule	Nucleus Nucleoplasm Nucleolus Preribosome Small-subunit Processome Mpp10 Complex
	Molecular Function	Protein Binding Signaling Receptor Activity	RNA Binding Protein Binding RRNA Binding SnoRNA Binding
	Biological Process	Signal Transduction Negative Regulation Of Epithelial Cell Migration Wnt Signaling Pathway Establishment Of Protein Localization Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Canonical Wnt Signaling Pathway	RRNA Processing
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Adult body size ( 32376654) Brain cytoarchitecture ( 20308991) Cerebral amyloid angiopathy ( 25188341) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Height ( 31562340) Metabolite levels ( 23823483) Neurofibrillary tangles ( 31497858) Nicotine dependence symptom count ( 25555482) Triglyceride levels ( 32203549)
Interacting Genes		79 interacting genes: ALDOB ANP32B APP BAAT C8orf33 C8orf48 CBX5 CBX8 CCDC112 CCDC146 CCDC180 CCDC185 CCDC187 CDC14B CDK8 CDKL3 CEP57L1 CEP95 CFAP58 CSNK1E CYLC2 DNAAF4 DYNC1I1 ELOA ERBIN ESRRG FAM161A FGF16 FRAT2 GTF2E2 HEMGN HSD17B3 IMP3 KAT5 KIF3C KIFC3 LRRC45 MAGEE1 MSANTD3 MTNR1A NANS NEK2 NFKBIB NOL12 PCCA PNKP POLL PRPF18 RASAL2 RCOR3 SEC61B SFRP4 SLTM SLU7 SYT17 SYT6 TCEA2 TCEANC TGFB1 THAP7 TRMO TRMT2A TSHZ2 TSTD2 TXLNA UTP14C ZBTB48 ZNF12 ZNF189 ZNF202 ZNF264 ZNF3 ZNF35 ZNF417 ZNF438 ZNF497 ZNF543 ZNF648 ZNF792	15 interacting genes: CCNDBP1 EFHC1 EVI5 KLC3 LPXN MCC MPHOSPH10 NANOS3 PPP1R12C SERTAD3 SORBS3 TFIP11 USHBP1 ZNF655 ZYX
Entrez ID		4163	55272
HPRD ID		01157	12664
Ensembl ID		ENSG00000171444	ENSG00000177971
Uniprot IDs		P23508	Q9NV31
PDB IDs		6MTU 6MTV	2CQJ
Enriched GO Terms of Interacting Partners?
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