MAOB and FGF14

Data Source:
BioGRID (two hybrid)

		MAOB	FGF14
Description		monoamine oxidase B	fibroblast growth factor 14
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Integral Component Of Membrane	Extracellular Region Nucleus Cytoplasm
	Molecular Function	Protein Binding Primary Amine Oxidase Activity Electron Transfer Activity Identical Protein Binding Flavin Adenine Dinucleotide Binding	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity
	Biological Process	Response To Toxic Substance Response To Aluminum Ion Response To Selenium Ion Negative Regulation Of Serotonin Secretion Substantia Nigra Development Electron Transport Chain Response To Lipopolysaccharide Neurotransmitter Catabolic Process Dopamine Catabolic Process Response To Drug Response To Ethanol Positive Regulation Of Dopamine Metabolic Process Hydrogen Peroxide Biosynthetic Process Response To Corticosterone	Signal Transduction Cell-cell Signaling Nervous System Development Regulation Of Synaptic Plasticity Regulation Of Postsynaptic Membrane Potential Positive Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Synaptic Vesicle Recycling Regulation Of Voltage-gated Sodium Channel Activity
Pathways		Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB	Phase 0 - rapid depolarisation
Drugs		Amphetamine Amphetamine Phentermine Procaine Tranylcypromine Phenelzine Zonisamide Selegiline Pioglitazone Procarbazine Moclobemide Moclobemide Isocarboxazid Ephedra sinica root Rasagiline MMDA 4-Methoxyamphetamine Metamfetamine Pargyline Isatin (R)-N-methyl-N-2-propynyl-1-indanamine Farnesol N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate Flavin adenine dinucleotide N-Propargyl-1(S)-Aminoindan Dodecyldimethylamine N-oxide 5-Hydroxy-N-Propargyl-1(R)-Aminoindan N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE Nialamide Nomifensine Zimelidine Safinamide 7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE 7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE (1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE 4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN (S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE] Flortaucipir F-18
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS			Bone mineral density (hip) ( 30172743) Idiopathic downbeat nystagmus ( 32157568) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Maximum habitual alcohol consumption ( 31151762) Plasma parathyroid hormone levels ( 30134803) PR interval ( 32439900) Preeclampsia ( 23551011) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes		6 interacting genes: COX20 FGF14 NFYB RHBDD2 SRPK1 TRIM54	13 interacting genes: ACACA EHHADH FBXO34 FKBP8 FUNDC2 H4C7 HOXD12 MAOB RTP5 SCN8A SMC1A SYT16 TTPA
Entrez ID		4129	2259
HPRD ID		02401	03305
Ensembl ID		ENSG00000069535	ENSG00000102466
Uniprot IDs		B7Z242 P27338	Q92915
PDB IDs		1GOS 1H8R 1OJ9 1OJA 1OJC 1OJD 1S2Q 1S2Y 1S3B 1S3E 2BK3 2BK4 2BK5 2BYB 2C64 2C65 2C66 2C67 2C70 2C72 2C73 2C75 2C76 2V5Z 2V60 2V61 2VRL 2VRM 2VZ2 2XCG 2XFN 2XFO 2XFP 2XFQ 2XFU 3PO7 3ZYX 4A79 4A7A 4CRT 5MRL 6FVZ 6FW0 6FWC 6RKB 6RKP 6RLE 6YT2
Enriched GO Terms of Interacting Partners?
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