FGF14 and RTP5

Data Source:
BioGRID (two hybrid)

		FGF14	RTP5
Description		fibroblast growth factor 14	receptor transporter protein 5 (putative)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm	Integral Component Of Membrane
	Molecular Function	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity	Protein Binding Olfactory Receptor Binding
	Biological Process	Signal Transduction Cell-cell Signaling Nervous System Development Regulation Of Synaptic Plasticity Regulation Of Postsynaptic Membrane Potential Positive Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Synaptic Vesicle Recycling Regulation Of Voltage-gated Sodium Channel Activity	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Protein Targeting To Membrane Protein Insertion Into Membrane
Pathways		Phase 0 - rapid depolarisation	Olfactory Signaling Pathway
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Bone mineral density (hip) ( 30172743) Idiopathic downbeat nystagmus ( 32157568) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Maximum habitual alcohol consumption ( 31151762) Plasma parathyroid hormone levels ( 30134803) PR interval ( 32439900) Preeclampsia ( 23551011) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes		13 interacting genes: ACACA EHHADH FBXO34 FKBP8 FUNDC2 H4C7 HOXD12 MAOB RTP5 SCN8A SMC1A SYT16 TTPA	51 interacting genes: ACTN2 ACTN3 AKAP8L APOC1 ASPG BEND5 BPIFA1 CALCOCO2 CARD9 CBY2 CIDEB COG6 DOCK8 EIF3F FGF14 GOLGA2 GOLGA6L9 HNRNPK HSF2BP KIFAP3 KRT27 KRT31 KRT33B KRT34 KRT40 KRT86 KRTAP19-5 KRTAP6-2 LZTS2 MDFI MIPOL1 MIS18A MKRN3 MTUS2 NFKBID PDE4DIP PNMA1 PNMA2 PSMA3 PSMA6 PSTPIP1 RBPMS RINT1 ROPN1 SERTAD3 SP100 SPDL1 TRAF1 TRIM23 TSGA10 USHBP1
Entrez ID		2259	285093
HPRD ID		03305	08159
Ensembl ID		ENSG00000102466	ENSG00000188011
Uniprot IDs		Q92915	Q14D33
PDB IDs
Enriched GO Terms of Interacting Partners?
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