MAGEB2 and ECSIT

		MAGEB2	ECSIT
Description		MAGE family member B2	ECSIT signaling integrator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Mitochondrial Respiratory Chain Complex I Assembly Innate Immune Response Regulation Of Oxidoreductase Activity Regulation Of Protein Complex Stability
Pathways			MyD88:MAL(TIRAP) cascade initiated on plasma membrane Complex I biogenesis TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation MyD88 cascade initiated on plasma membrane
Drugs
Diseases
GWAS			Presence of antiphospholipid antibodies ( 27098658)
Interacting Genes		8 interacting genes: ARID3A ATXN1 CCNL2 ECSIT PRMT5 RPGRIP1 TXN2 ZBED1	52 interacting genes: A2M AP1M2 APOE APP BFSP2 BLMH C1orf109 CDC37 CEP55 CTNNA3 CYP2C18 CYP2C8 CYP2C9 DNAJB1 DTX2 ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 GCDH GEM IFIT3 IFIT5 IMMT LONP1 LOXL4 MAGEB2 MAST1 MKRN3 NFKB1 NXF1 PAXIP1 PI4K2A PRDX2 PSEN1 RAB3A RAD23A RELA RHEB RNF32 SETDB1 SMAD1 SMAD4 SMURF1 STAMBPL1 STRN4 TARS3 TRAF6 TRIM59 TSSK3
Entrez ID		4113	51295
HPRD ID		02109	12225
Ensembl ID		ENSG00000099399	ENSG00000130159
Uniprot IDs		O15479 Q53G50	Q9BQ95
PDB IDs
Enriched GO Terms of Interacting Partners?
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