MIR199A1 and DDX49

Data Source:
BioGRID (unspecified method)

		MIR199A1	DDX49
Description		microRNA 199a-1	DEAD-box helicase 49
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Nucleus Nucleoplasm
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding RNA Helicase Activity Protein Binding ATP Binding
	Biological Process	Re-entry Into Mitotic Cell Cycle Negative Regulation Of Receptor Internalization Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Autophagy Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of TOR Signaling Negative Regulation Of Hepatocyte Growth Factor Production Gene Silencing By MiRNA Negative Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Angiogenesis Positive Regulation Of Angiogenesis Positive Regulation Of Protein Kinase B Signaling Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Lung Blood Pressure Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Metallopeptidase Activity Positive Regulation Of Cardiac Muscle Tissue Regeneration Regulation Of Connective Tissue Replacement Positive Regulation Of Connective Tissue Replacement	RRNA Processing Positive Regulation Of Cell Growth Regulation Of RRNA Stability
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Cerebrospinal fluid p-Tau181p:AB1-42 ratio ( 26252872) Cerebrospinal P-tau181p levels ( 26252872)
Interacting Genes		83 interacting genes: AIMP1 AIMP2 C1QBP CELF1 CELF2 CPSF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX3X DDX49 DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SAFB SF3A3 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 STRBP SYMPK SYNCRIP TAF15 TIAL1 TRA2A TRA2B UPF1 UTP20 YBX1 YBX2 YBX3	11 interacting genes: APP HAP1 MIR1-2 MIR138-2 MIR140 MIR15A MIR199A1 MIR214 PAGE1 PSMB2 STX1A
Entrez ID		406976	54555
HPRD ID			10864
Ensembl ID		ENSG00000207752	ENSG00000105671
Uniprot IDs			Q9Y6V7
PDB IDs
Enriched GO Terms of Interacting Partners?
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