LTBP3 and CCNG1

Data Source:
BioGRID (two hybrid)

		LTBP3	CCNG1
Description		latent transforming growth factor beta binding protein 3	cyclin G1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen-containing Extracellular Matrix Extracellular Exosome	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Calcium Ion Binding Protein Binding Transforming Growth Factor Beta Binding	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process	Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Bone Mineralization Negative Regulation Of Chondrocyte Differentiation Transforming Growth Factor Beta Activation Positive Regulation Of Bone Resorption Bone Remodeling Elastic Fiber Assembly Bone Morphogenesis Lung Saccule Development Positive Regulation Of Mesenchymal Stem Cell Proliferation Positive Regulation Of Mesenchymal Stem Cell Differentiation	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mitotic Cell Cycle Phase Transition Cell Division
Pathways		Molecules associated with elastic fibres	Regulation of TP53 Degradation
Drugs
Diseases		Tooth agenesis; Hypodontia
GWAS		Acne (severe) ( 24927181) Eosinophil counts ( 32888494) Heel bone mineral density ( 30598549) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Non-alcoholic fatty liver disease histology (lobular) ( 20708005) Osteoarthritis (hip) ( 30374069) Refractive error ( 32231278) Urate levels ( 23263486) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	HIV progression (CD4 and viral load) ( 28132517) Metabolite levels ( 31628463) Plasma anti-thyroglobulin levels ( 29678681) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		12 interacting genes: CACNA1A CCNG1 GORASP2 HBEGF ITGB5 PELI2 PIK3R2 PRPF40A RAC1 TGFB1 TGFB2 TGFB3	28 interacting genes: APP CBY2 CCDC125 CDK5 CDKN2A GAK GAS8 GRN HMBOX1 KRT40 KRTAP10-7 LMNA LTBP3 LZTS2 MDM2 MT-CO2 NFATC4 PAK5 PLEKHA4 PNMA1 PPP2CA PTPA RBPMS SHKBP1 TFAP2C TFIP11 TNIP1 TP53
Entrez ID		4054	900
HPRD ID		03649	03345
Ensembl ID		ENSG00000168056	ENSG00000113328
Uniprot IDs		B9EG76 Q8WYU6 Q9NS15	P51959
PDB IDs
Enriched GO Terms of Interacting Partners?
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