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LRP4 and WHRN
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
LRP4
WHRN
Description
LDL receptor related protein 4
whirlin
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Cell Surface
Postsynaptic Density
Integral Component Of Membrane
Dendrite
Neuromuscular Junction
Neuronal Cell Body
Plasma Membrane Raft
Synaptic Membrane
Photoreceptor Inner Segment
Stereocilia Ankle Link
Stereocilia Ankle Link Complex
Cytoplasm
Actin Filament
Plasma Membrane
Growth Cone
Photoreceptor Connecting Cilium
Stereocilium
Stereocilium Tip
Ciliary Basal Body
Neuronal Cell Body
Synapse
Periciliary Membrane Compartment
USH2 Complex
Molecular Function
Calcium Ion Binding
Protein Binding
Receptor Tyrosine Kinase Binding
Apolipoprotein Binding
Protein Homodimerization Activity
Scaffold Protein Binding
Protein Binding
Identical Protein Binding
Biological Process
Kidney Development
Hair Follicle Development
Endocytosis
Dorsal/ventral Pattern Formation
Proximal/distal Pattern Formation
Wnt Signaling Pathway
Negative Regulation Of Ossification
Odontogenesis Of Dentin-containing Tooth
Embryonic Digit Morphogenesis
Dendrite Morphogenesis
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Negative Regulation Of Axonogenesis
Synapse Organization
Synaptic Growth At Neuromuscular Junction
Limb Development
Skeletal Muscle Acetylcholine-gated Channel Clustering
Negative Regulation Of Canonical Wnt Signaling Pathway
Postsynaptic Membrane Assembly
Presynaptic Membrane Assembly
Amyloid-beta Clearance By Cellular Catabolic Process
Positive Regulation Of Presynaptic Membrane Organization
Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering
Retina Homeostasis
Sensory Perception Of Sound
Positive Regulation Of Gene Expression
Cerebellar Purkinje Cell Layer Formation
Establishment Of Protein Localization
Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound
Sensory Perception Of Light Stimulus
Auditory Receptor Cell Stereocilium Organization
Inner Ear Receptor Cell Stereocilium Organization
Paranodal Junction Maintenance
Pathways
ECM proteoglycans
Drugs
Diseases
Cenani-Lenz syndactyly syndrome
Usher syndrome (US)
Deafness, autosomal recessive
GWAS
Alzheimer's disease or fasting glucose levels (pleiotropy) (
30805717
)
Autism spectrum disorder or schizophrenia (
28540026
)
Bone mineral density (hip) (
19079262
)
D-dimer levels (
21502573
)
General risk tolerance (MTAG) (
30643258
)
HDL cholesterol (
24097068
20686565
)
HDL cholesterol levels (
28334899
)
Heel bone mineral density (
30598549
28869591
)
Intraocular pressure (
29617998
)
Mood instability (
31168069
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Reaction time (
29844566
)
Systolic blood pressure (
30224653
)
Urate levels (
31578528
)
Venous thromboembolism (
31420334
)
Interacting Genes
1 interacting genes:
WHRN
17 interacting genes:
BEND7
BMI1
CASK
COL17A1
EFHC1
GOLGA2
GPSM2
HEMGN
KEAP1
LRP4
LRRC4C
MYO15A
MYO7A
PXN
RPS6KA1
SPC24
TPRN
Entrez ID
4038
25861
HPRD ID
18517
09718
Ensembl ID
ENSG00000134569
ENSG00000095397
Uniprot IDs
O75096
B9EGE6
Q9P202
PDB IDs
1UEZ
1UF1
1UFX
6KZ1
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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