WHRN and GPSM2

Data Source:
BioGRID (two hybrid)

		WHRN	GPSM2
Description		whirlin	G protein signaling modulator 2
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GO Annotations	Cellular Component	Photoreceptor Inner Segment Stereocilia Ankle Link Stereocilia Ankle Link Complex Cytoplasm Actin Filament Plasma Membrane Growth Cone Photoreceptor Connecting Cilium Stereocilium Stereocilium Tip Ciliary Basal Body Neuronal Cell Body Synapse Periciliary Membrane Compartment USH2 Complex	Cytoplasm Centrosome Cytosol Cell Cortex Lateral Plasma Membrane Protein-containing Complex Mitotic Spindle Pole Lateral Cell Cortex Cell Cortex Region
	Molecular Function	Protein Binding Identical Protein Binding	Nucleotide Binding GDP-dissociation Inhibitor Activity Protein Binding Protein C-terminus Binding Protein Domain Specific Binding Identical Protein Binding Protein Self-association Dynein Complex Binding
	Biological Process	Retina Homeostasis Sensory Perception Of Sound Positive Regulation Of Gene Expression Cerebellar Purkinje Cell Layer Formation Establishment Of Protein Localization Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Sensory Perception Of Light Stimulus Auditory Receptor Cell Stereocilium Organization Inner Ear Receptor Cell Stereocilium Organization Paranodal Junction Maintenance	Establishment Of Mitotic Spindle Orientation Mitotic Spindle Organization G Protein-coupled Receptor Signaling Pathway Ran Protein Signal Transduction Regulation Of Catalytic Activity Cell Division Maintenance Of Centrosome Location Regulation Of Mitotic Spindle Organization Positive Regulation Of Protein Localization To Cell Cortex Positive Regulation Of Spindle Assembly
Pathways			G alpha (i) signalling events
Drugs
Diseases		Usher syndrome (US) Deafness, autosomal recessive
GWAS			Fat distribution (HIV) ( 21897333)
Interacting Genes		17 interacting genes: BEND7 BMI1 CASK COL17A1 EFHC1 GOLGA2 GPSM2 HEMGN KEAP1 LRP4 LRRC4C MYO15A MYO7A PXN RPS6KA1 SPC24 TPRN	13 interacting genes: AGR2 ARHGEF40 GAS2L1 GLIS2 GNAI1 GNAI2 GNAI3 GNAO1 HRAS INSC LRRC8E NUMA1 WHRN
Entrez ID		25861	29899
HPRD ID		09718	06609
Ensembl ID		ENSG00000095397	ENSG00000121957
Uniprot IDs		B9EGE6 Q9P202	A0A024R0F8 B4DIF1 P81274
PDB IDs		1UEZ 1UF1 1UFX 6KZ1	3SF4 4WND 4WNE 4WNF 4WNG 5A6C 6HC2
Enriched GO Terms of Interacting Partners?
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