LOX and MYL4

Data Source:
BioGRID (affinity chromatography technology)

		LOX	MYL4
Description		lysyl oxidase	myosin light chain 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Nucleus Extracellular Matrix	Cytosol Myosin Complex A Band
	Molecular Function	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding Collagen Binding	Actin Monomer Binding Calcium Ion Binding Myosin II Heavy Chain Binding Actin Filament Binding
	Biological Process	Osteoblast Differentiation Regulation Of Protein Phosphorylation Cellular Protein Modification Process Heart Development Regulation Of Gene Expression Regulation Of Striated Muscle Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-lysine Oxidation Protein Phosphopantetheinylation Extracellular Matrix Organization Collagen Fibril Organization Bone Mineralization Lung Development Platelet-derived Growth Factor Receptor-beta Signaling Pathway Ascending Aorta Development Descending Aorta Development Wound Healing Response To Drug Regulation Of Apoptotic Process Protein Kinase B Signaling Regulation Of Megakaryocyte Differentiation Muscle Cell Cellular Homeostasis Elastic Fiber Assembly Blood Vessel Morphogenesis Response To Steroid Hormone Muscle Fiber Development Cell Chemotaxis Connective Tissue Development DNA Biosynthetic Process Regulation Of Receptor Binding Regulation Of Bone Development Cellular Response To Chemokine Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway	Regulation Of The Force Of Heart Contraction Muscle Filament Sliding Positive Regulation Of ATPase Activity Cardiac Muscle Contraction
Pathways		Elastic fibre formation Crosslinking of collagen fibrils	Striated Muscle Contraction
Drugs
Diseases
GWAS		Central corneal thickness ( 32528159) Coronary artery disease ( 28714974) Intraocular pressure ( 29617998) Lung function (FEV1/FVC) ( 30804560) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Youthful appearance (self-reported) ( 32339537)	Body mass index ( 26426971) Erythema nodosum in inflammatory bowel disease ( 24487271)
Interacting Genes		8 interacting genes: DHDDS DPT ELN H1-1 H1-5 H2BC11 H2BC21 RAF1	1 interacting genes: PYROXD2
Entrez ID		4015	4635
HPRD ID		01087	01176
Ensembl ID		ENSG00000113083	ENSG00000198336
Uniprot IDs		B0AZT2 B7ZAJ4 D0PNI2 P28300	P12829
PDB IDs
Enriched GO Terms of Interacting Partners?
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