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LOX and H1-5
Data Source:
HPRD
(in vitro)
LOX
H1-5
Description
lysyl oxidase
H1.5 linker histone, cluster member
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Collagen Trimer
Extracellular Space
Nucleus
Extracellular Matrix
Chromatin
Nucleosome
Heterochromatin
Nucleus
Molecular Function
Protein-lysine 6-oxidase Activity
Copper Ion Binding
Protein Binding
Collagen Binding
Double-stranded DNA Binding
RNA Binding
Protein Binding
Chromatin DNA Binding
Nucleosomal DNA Binding
Histone Deacetylase Binding
Biological Process
Osteoblast Differentiation
Regulation Of Protein Phosphorylation
Cellular Protein Modification Process
Heart Development
Regulation Of Gene Expression
Regulation Of Striated Muscle Tissue Development
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Peptidyl-lysine Oxidation
Protein Phosphopantetheinylation
Extracellular Matrix Organization
Collagen Fibril Organization
Bone Mineralization
Lung Development
Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Ascending Aorta Development
Descending Aorta Development
Wound Healing
Response To Drug
Regulation Of Apoptotic Process
Protein Kinase B Signaling
Regulation Of Megakaryocyte Differentiation
Muscle Cell Cellular Homeostasis
Elastic Fiber Assembly
Blood Vessel Morphogenesis
Response To Steroid Hormone
Muscle Fiber Development
Cell Chemotaxis
Connective Tissue Development
DNA Biosynthetic Process
Regulation Of Receptor Binding
Regulation Of Bone Development
Cellular Response To Chemokine
Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Nucleosome Assembly
Nucleosome Positioning
Chromosome Condensation
Positive Regulation Of Cell Growth
Negative Regulation Of Chromatin Silencing
Negative Regulation Of DNA Recombination
Protein Stabilization
Positive Regulation Of Histone H3-K9 Methylation
Establishment Of Protein Localization To Chromatin
Pathways
Elastic fibre formation
Crosslinking of collagen fibrils
Apoptosis induced DNA fragmentation
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS
Central corneal thickness (
32528159
)
Coronary artery disease (
28714974
)
Intraocular pressure (
29617998
)
Lung function (FEV1/FVC) (
30804560
)
Thiazide-induced adverse metabolic effects in hypertensive patients (
23400010
)
Youthful appearance (self-reported) (
32339537
)
Interacting Genes
8 interacting genes:
DHDDS
DPT
ELN
H1-1
H1-5
H2BC11
H2BC21
RAF1
31 interacting genes:
CBX5
CCNA1
CCNA2
CCNB1
CCNE1
CDC42
CDK1
CDK2
CDK5
CDKN1A
CDKN1B
EHMT2
HPF1
IRAK4
KAT2A
KAT2B
L3MBTL1
LOX
MELK
MLLT1
NSD1
PARP1
PARP2
PRKCA
PRKCB
PRKCD
PRKCZ
RIPK3
RPS6KA5
SERPINH1
SIRT1
Entrez ID
4015
3009
HPRD ID
01087
00821
Ensembl ID
ENSG00000113083
ENSG00000184357
Uniprot IDs
B0AZT2
B7ZAJ4
D0PNI2
P28300
P16401
PDB IDs
2FE2
2RHI
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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