RHOH and MTX2

Data Source:
BioGRID (two hybrid)

		RHOH	MTX2
Description		ras homolog family member H	metaxin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle	SAM Complex Nucleolus Cytoplasm Mitochondrion Mitochondrial Outer Membrane MIB Complex
	Molecular Function	GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding Kinase Inhibitor Activity Protein Kinase Binding Small GTPase Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Motor Neuron Axon Guidance Regulation Of Cell Shape Rac Protein Signal Transduction Cell Projection Assembly T Cell Differentiation Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Kinase Activity Negative Regulation Of GTPase Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Engulfment Of Apoptotic Cell Mast Cell Activation Positive Regulation Of T Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Neutrophil Migration	Mitochondrial Transport Mitochondrion Organization Inner Mitochondrial Membrane Organization Protein Transport
Pathways		Rho GTPase cycle	Mitochondrial protein import Cristae formation
Drugs
Diseases
GWAS		Graves' disease ( 21841780) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)	Blond vs. brown/black hair color ( 30531825) Blood urea nitrogen levels ( 31152163) Chin dimples ( 27182965) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate in non-diabetics ( 31451708) Eye morphology ( 29921221) Male-pattern baldness ( 27182965 28196072) Monobrow ( 27182965) Upper eyelid morphology ( 29921221) Urate levels ( 31578528)
Interacting Genes		23 interacting genes: ARHGDIA ARHGDIB ARHGDIG BANP CCNH FAM90A1 GDI1 IQUB ITGB1BP1 KANK2 KCNH2 LRIF1 MBLAC1 MTX2 PLEKHA7 RIPPLY1 SCNM1 SORL1 SUOX TCF19 TGFBR1 UTP14A XPNPEP1	6 interacting genes: C1QTNF2 KASH5 MTX1 RHOH TADA2A UBQLN2
Entrez ID		399	10651
HPRD ID		03616	09777
Ensembl ID		ENSG00000168421	ENSG00000128654
Uniprot IDs		Q15669 Q6ICP4	O75431
PDB IDs
Enriched GO Terms of Interacting Partners?
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