LIG4 and EIF4G3

  • Data Source:
  • BioGRID (two hybrid)

LIG4

EIF4G3

Description DNA ligase 4 eukaryotic translation initiation factor 4 gamma 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
  • Irritable bowel syndrome ( 29626450)
  • Basophil count ( 32888494)
  • Basophil percentage of white cells ( 32888494)
  • Chronotype ( 30696823)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • General risk tolerance (MTAG) ( 30643258)
  • Mean spheric corpuscular volume ( 32888494)
  • Morning person ( 30696823)
  • Postoperative acute renal failure after cardiac surgery ( 30678657)
  • Red blood cell count ( 32888494)
  • Social science traits (pleiotropy) (HIPO component 1) ( 30289880)
  • Superior frontal gyrus grey matter volume ( 25335168)
Interacting Genes 103 interacting genes: ACTG1 AFTPH AGAP4 ALMS1 AMZ2P1 ANAPC10 APLF ASPM ATM ATP6V0D1 ATR B9D1 BBOF1 CAP1 CLU COL1A2 COMMD1 CPNE1 CREBBP CTSK DDX19A DGUOK DPP3 EIF2AK1 EIF3I EIF4A1 EIF4G3 ENO1 ETF1 FAM214A FBLL1 FIP1L1 GAPDH GGH GPANK1 GRHPR GUSBP3 GZMK HMGN1 HNRNPA2B1 IPP KDELR1 KIF3A LAP3 MAP2K2 MCM4 MCRS1 MRPS18C MT-CO1 MT-CO2 MT-CO3 MT-ND1 MT-ND4 MT-ND5 NDUFA13 NDUFB10 NEU1 NHEJ1 NOMO3 NPC2 OGFOD1 OSTM1 OXR1 PA2G4 PALLD PEX10 PGP PHF10 PMS2P1 PPIA PRKDC PSMA6 RBM5 RHBDD2 RPL11 RPS19BP1 RUVBL2 SEMA4G SMC2 SNX3 SOWAHC SRSF2 SYCP3 THOC5 TLE4 TOP1 TP53BP1 TPT1 TRAPPC3 TSFM UBB UBE2L3 UFSP2 UNC119 VKORC1 WARS1 WBP1L WDR20 XRCC4 ZFAND2A ZNF428 ZSCAN18 ZWINT 8 interacting genes: CAMK1 EIF4A1 EIF4E HSPB1 LIG4 MKNK1 PABPC1 VAV2
Entrez ID 3981 8672
HPRD ID 03500 06802
Ensembl ID ENSG00000174405 ENSG00000075151
Uniprot IDs A0A024RE06 A0A0C4DGV9 A8K8Q4 P49917 A0A0A0MSA7 O43432 Q59GJ0
PDB IDs 1IK9 2E2W 3II6 3VNN 3W1B 3W1G 3W5O 4HTO 4HTP 6BKF 6BKG 1HU3
Enriched GO Terms of Interacting Partners?
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