LAMA5 and SV2A

Data Source:
HPRD (in vivo)

		LAMA5	SV2A
Description		laminin subunit alpha 5	synaptic vesicle glycoprotein 2A
Image
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-5 Complex Extracellular Space Nucleus Neuromuscular Junction Synaptic Cleft Laminin-10 Complex Laminin-11 Complex Collagen-containing Extracellular Matrix Extracellular Exosome	Endoplasmic Reticulum Plasma Membrane Cell-cell Junction Synaptic Vesicle Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane Dendrite Synaptic Vesicle Membrane Neuromuscular Junction Neuron Projection Neuronal Cell Body Presynaptic Active Zone Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Integrin Binding Extracellular Matrix Structural Constituent	Protein Kinase Binding Transmembrane Transporter Activity
	Biological Process	Branching Involved In Ureteric Bud Morphogenesis Morphogenesis Of A Polarized Epithelium Neural Crest Cell Migration Hair Follicle Development Integrin-mediated Signaling Pathway Axon Guidance Muscle Organ Development Animal Organ Morphogenesis Tissue Development Morphogenesis Of Embryonic Epithelium Cell Migration Cytokine-mediated Signaling Pathway Regulation Of Cell Adhesion Extracellular Matrix Organization Lung Development Regulation Of Cell Migration Substrate Adhesion-dependent Cell Spreading Regulation Of Cell Population Proliferation Odontogenesis Of Dentin-containing Tooth Regulation Of Embryonic Development Cilium Assembly Branching Involved In Salivary Gland Morphogenesis Protein Localization To Plasma Membrane Cell-cell Adhesion	Cellular Calcium Ion Homeostasis Regulation Of Gamma-aminobutyric Acid Secretion Synaptic Vesicle Priming Transmembrane Transport
Pathways		Degradation of the extracellular matrix Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Interleukin-4 and Interleukin-13 signaling MET activates PTK2 signaling	Toxicity of botulinum toxin type D (botD) Toxicity of botulinum toxin type A (botA) Toxicity of botulinum toxin type F (botF) Toxicity of botulinum toxin type E (botE)
Drugs		Lanoteplase	Levetiracetam Brivaracetam Seletracetam
Diseases
GWAS		Blood protein levels ( 29875488) Colorectal cancer ( 25990418 20972440 24737748) Colorectal cancer or advanced adenoma ( 30510241) Estimated glomerular filtration rate ( 31152163) Neuroblastoma (pediatric) ( 32599975) Pelvic organ prolapse ( 26545240) Plateletcrit ( 32888494) Prostate cancer ( 23535732)	Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Height ( 25429064 31562340 18391951) Lung function (FEV1) ( 26635082)
Interacting Genes		15 interacting genes: ATF7IP BCAM BTBD10 COL7A1 CRKL DAG1 FBLN2 LAMC1 MEP1A MTDH MYOC SMAD2 SV2A UBC USP4	4 interacting genes: ATXN1 DNAJC5 LAMA5 LTB4R2
Entrez ID		3911	9900
HPRD ID		03020	08922
Ensembl ID		ENSG00000130702	ENSG00000159164
Uniprot IDs		O15230	B4E000 Q7L0J3
PDB IDs		5XAU	4V11
Enriched GO Terms of Interacting Partners?
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