LAMA5 and FBLN2

Data Source:
HPRD (in vivo, in vitro)

		LAMA5	FBLN2
Description		laminin subunit alpha 5	fibulin 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-5 Complex Extracellular Space Nucleus Neuromuscular Junction Synaptic Cleft Laminin-10 Complex Laminin-11 Complex Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Vesicle
	Molecular Function	Integrin Binding Extracellular Matrix Structural Constituent	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding
	Biological Process	Branching Involved In Ureteric Bud Morphogenesis Morphogenesis Of A Polarized Epithelium Neural Crest Cell Migration Hair Follicle Development Integrin-mediated Signaling Pathway Axon Guidance Muscle Organ Development Animal Organ Morphogenesis Tissue Development Morphogenesis Of Embryonic Epithelium Cell Migration Cytokine-mediated Signaling Pathway Regulation Of Cell Adhesion Extracellular Matrix Organization Lung Development Regulation Of Cell Migration Substrate Adhesion-dependent Cell Spreading Regulation Of Cell Population Proliferation Odontogenesis Of Dentin-containing Tooth Regulation Of Embryonic Development Cilium Assembly Branching Involved In Salivary Gland Morphogenesis Protein Localization To Plasma Membrane Cell-cell Adhesion	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways		Degradation of the extracellular matrix Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Interleukin-4 and Interleukin-13 signaling MET activates PTK2 signaling	Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs		Lanoteplase
Diseases
GWAS		Blood protein levels ( 29875488) Colorectal cancer ( 25990418 20972440 24737748) Colorectal cancer or advanced adenoma ( 30510241) Estimated glomerular filtration rate ( 31152163) Neuroblastoma (pediatric) ( 32599975) Pelvic organ prolapse ( 26545240) Plateletcrit ( 32888494) Prostate cancer ( 23535732)	Bipolar disorder with mood-incongruent psychosis ( 23092984) Body mass index ( 26426971) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes		15 interacting genes: ATF7IP BCAM BTBD10 COL7A1 CRKL DAG1 FBLN2 LAMC1 MEP1A MTDH MYOC SMAD2 SV2A UBC USP4	30 interacting genes: ACAN ATN1 BCAN COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL8A1 ELN ERCC6 FBN1 FBXW5 FN1 HSD3B7 HSPG2 ITGB3 JOSD1 LAMA1 LAMA5 LAMC2 LCE3D NID1 OTX1 PRELP VCAN ZNF408 ZNF414
Entrez ID		3911	2199
HPRD ID		03020	00630
Ensembl ID		ENSG00000130702	ENSG00000163520
Uniprot IDs		O15230	P98095 Q86V58 Q9Y3V7
PDB IDs		5XAU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?