LAMA3 and SLC35E1

Data Source:
HPRD (two hybrid)

		LAMA3	SLC35E1
Description		laminin subunit alpha 3	solute carrier family 35 member E1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-5 Complex Endoplasmic Reticulum Collagen-containing Extracellular Matrix Extracellular Exosome	Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent	Protein Binding Antiporter Activity
	Biological Process	Morphogenesis Of A Polarized Epithelium Integrin-mediated Signaling Pathway Axon Guidance Epidermis Development Animal Organ Morphogenesis Tissue Development Cell Migration Regulation Of Cell Adhesion Extracellular Matrix Organization Regulation Of Cell Migration Hemidesmosome Assembly Endodermal Cell Differentiation Regulation Of Embryonic Development Cell-cell Adhesion	Transmembrane Transport
Pathways		Degradation of the extracellular matrix Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Anchoring fibril formation Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Type I hemidesmosome assembly MET activates PTK2 signaling
Drugs		Lanoteplase
Diseases		Laryngoonychocutaneous syndrome Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA) Epidermolysis bullosa, hemidesmosomal, including: Epidermolysis bullosa, generalized atrophic benign (GABEB); Epidermolysis bullosa simplex with pyloric atresia (EBS-PA); Epidermolysis bullosa simplex with muscular dystrophy (EBS-MD); Epidermolysis bullosa simplex, Ogna type (EBS-Ogna)
GWAS		Allergic rhinitis ( 25085501) Amyotrophic lateral sclerosis ( 22959728) Composite immunoglobulin trait (IgA x IgG/IgM) ( 28628107) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252)
Interacting Genes		7 interacting genes: APC BMP1 LAMB3 PLAT PLG SDC2 SLC35E1	6 interacting genes: ABCF3 FTHL17 FXYD6 LAMA3 MCOLN1 MPP1
Entrez ID		3909	79939
HPRD ID		02883	15373
Ensembl ID		ENSG00000053747	ENSG00000127526
Uniprot IDs		A0A0A0MSA0 A0A0A0MTS5 A0A0A6YYF2 Q16787	A0A024R7G7 Q96K37
PDB IDs
Enriched GO Terms of Interacting Partners?
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