KRT19 and KRT6A

Data Source:
BioGRID (two hybrid)

		KRT19	KRT6A
Description		keratin 19	keratin 6A
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Plasma Membrane Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Z Disc Sarcolemma Costamere Extracellular Exosome Cell Periphery Terminal Web	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Protein-containing Complex Binding	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Notch Signaling Pathway Viral Process Keratinization Response To Estrogen Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development Cornification	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Cell Differentiation Keratinization Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cornification Negative Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases			Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS			Cutaneous squamous cell carcinoma ( 32041948)
Interacting Genes		79 interacting genes: ABI2 AMOT AMOTL2 APC ARL4A BEX2 C1orf109 CARD9 CCDC146 CCHCR1 CEP57L1 COPS4 DEPP1 DGCR6L DMD EIF4E2 EIF4ENIF1 ESR1 EXOC8 FAM107A FAM124B FANCG GFAP GLYCTK HAUS1 HGS IKZF3 KDM1A KIFC3 KRT1 KRT15 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LENG1 LGALS14 NFKBID PCDHB12 PCM1 PKN1 PLEKHA5 PNN POLL POLR1C PPP1R18 PRPH PSMA1 RCOR3 SFI1 SGF29 SMARCB1 SMARCE1 SNAPIN SPG21 TBC1D7 TCHP TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638	38 interacting genes: BEX2 CCDC85B DSP GEM GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT16 KRT17 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 LMNA MTUS2 NCALD NUP62 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 TXLNB UBQLN2 WASHC3
Entrez ID		3880	3853
HPRD ID		01007	01011
Ensembl ID		ENSG00000171345	ENSG00000205420
Uniprot IDs		P08727	A0A0S2Z428 P02538
PDB IDs			5KI0
Enriched GO Terms of Interacting Partners?
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