ASPG and VPS25

Data Source:
BioGRID (two hybrid)

		ASPG	VPS25
Description		asparaginase	vacuolar protein sorting 25 homolog
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	ESCRT II Complex Nucleus Nucleoplasm Cytoplasm Cytosol Endosome Membrane Extracellular Exosome
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Asparaginase Activity Lysophospholipase Activity Protein Binding Transferase Activity, Transferring Acyl Groups Other Than Amino-acyl Groups Phosphatidyl Phospholipase B Activity	Structural Molecule Activity Protein Binding Protein Homodimerization Activity Protein N-terminus Binding
	Biological Process	Cellular Amino Acid Biosynthetic Process Lipid Catabolic Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Endosomal Transport Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Pathways		Aspartate and asparagine metabolism	Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
Drugs		Procaine
Diseases
GWAS		Blood metabolite levels ( 24816252) Body mass index ( 26426971) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma free asparagine levels ( 30659259) Refractive error ( 32231278) Schizophrenia ( 29483656) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		12 interacting genes: C20orf85 CEACAM6 DMRT3 GSDMD MYOZ3 RTP5 SGK1 SHC3 TEKT3 TMEM115 USP2 VPS25	21 interacting genes: APIP ASPG B9D2 BEND5 BPIFA1 CHMP6 CRLF3 GPR35 LTB4R2 PICK1 REL RHOXF2 SDCBP2 SEPTIN14 SNF8 SPG21 SPRY2 SYCE1 TADA2A TRIM27 VPS36
Entrez ID		374569	84313
HPRD ID		19180	14396
Ensembl ID		ENSG00000166183	ENSG00000131475
Uniprot IDs		Q86U10	A0A024R1X3 Q9BRG1
PDB IDs			2ZME 3CUQ 3HTU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?