ASPG and TMEM115

Data Source:
BioGRID (two hybrid)

		ASPG	TMEM115
Description		asparaginase	transmembrane protein 115
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Golgi Membrane Nucleus Golgi Apparatus Integral Component Of Membrane Golgi Transport Complex Golgi Cisterna Membrane
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Asparaginase Activity Lysophospholipase Activity Protein Binding Transferase Activity, Transferring Acyl Groups Other Than Amino-acyl Groups Phosphatidyl Phospholipase B Activity	Molecular_function Protein Binding Identical Protein Binding
	Biological Process	Cellular Amino Acid Biosynthetic Process Lipid Catabolic Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Negative Regulation Of Cell Population Proliferation Protein Transport
Pathways		Aspartate and asparagine metabolism	COPI-mediated anterograde transport
Drugs		Procaine
Diseases
GWAS		Blood metabolite levels ( 24816252) Body mass index ( 26426971) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma free asparagine levels ( 30659259) Refractive error ( 32231278) Schizophrenia ( 29483656) Serum metabolite concentrations in chronic kidney disease ( 29545352)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		12 interacting genes: C20orf85 CEACAM6 DMRT3 GSDMD MYOZ3 RTP5 SGK1 SHC3 TEKT3 TMEM115 USP2 VPS25	12 interacting genes: AQP6 ASPG CREB3 CYB5R3 HTATIP2 MANBAL RABAC1 SYNE4 TLCD4 TMED8 TMX2 ZDHHC17
Entrez ID		374569	11070
HPRD ID		19180	06144
Ensembl ID		ENSG00000166183	ENSG00000126062
Uniprot IDs		Q86U10	A0A024R2Y2 Q12893
PDB IDs
Enriched GO Terms of Interacting Partners?
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