ITPKB and CTDSP1

Data Source:
BioGRID (two hybrid)

		ITPKB	CTDSP1
Description		inositol-trisphosphate 3-kinase B	CTD small phosphatase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane	Nucleus Nucleoplasm Extracellular Exosome
	Molecular Function	Inositol Hexakisphosphate Kinase Activity Protein Binding Calmodulin Binding ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity Kinase Activity	Phosphoprotein Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	MAPK Cascade Regulation Of Protein Phosphorylation Myeloid Cell Homeostasis Signal Transduction Cell Surface Receptor Signaling Pathway Inositol Trisphosphate Metabolic Process Inositol Phosphate Biosynthetic Process Negative Regulation Of Neutrophil Apoptotic Process Common Myeloid Progenitor Cell Proliferation Inositol Phosphate Metabolic Process Positive Thymic T Cell Selection Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Ras Protein Signal Transduction Positive Regulation Of Alpha-beta T Cell Differentiation Phosphatidylinositol Phosphorylation Cellular Response To Calcium Ion	Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation
Pathways		Synthesis of IP3 and IP4 in the cytosol
Drugs			Aspartate beryllium trifluoride Citric acid
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Dentures ( 31235808) Eosinophil percentage of white cells ( 32888494) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Parkinson's disease ( 32201043 28892059 32310270) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Subcutaneous adipose tissue ( 22589738)	Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 23128233) Mean corpuscular hemoglobin concentration ( 32888494 27863252)
Interacting Genes		13 interacting genes: CALM1 CEP70 CTDSP1 GOLGA2 IFT88 KRT34 PPP3CA PRKACA PRKCA PSME3 SCAI TRIM54 UBQLN2	35 interacting genes: ACTN3 BAG3 CDCA3 CDKN2C CRYBA2 CSF1R CSTF2T FAAP20 FAM110A FANCL FGFR2 GTF2F1 ITPKB LCK LDB1 MAPKBP1 MBP MORN3 NOXA1 OSTF1 PDZD4 POLR2A PPP1R32 PTPN11 RAB3IL1 SCNM1 SDCBP SNAI1 STRA8 TEKT4 TRAPPC6A TYRO3 WWOX YPEL5 ZBTB16
Entrez ID		3707	58190
HPRD ID		00942	05615
Ensembl ID		ENSG00000143772	ENSG00000144579
Uniprot IDs		B2R9J0 P27987	Q9GZU7
PDB IDs			1T9Z 1TA0 2GHQ 2GHT 3L0B 3L0C 3L0Y 3PGL 4YGY 4YH1 6DU3
Enriched GO Terms of Interacting Partners?
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