ITPKB

Description		inositol-trisphosphate 3-kinase B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane
	Molecular Function	Inositol Hexakisphosphate Kinase Activity Protein Binding Calmodulin Binding ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity Kinase Activity
	Biological Process	MAPK Cascade Regulation Of Protein Phosphorylation Myeloid Cell Homeostasis Signal Transduction Cell Surface Receptor Signaling Pathway Inositol Trisphosphate Metabolic Process Inositol Phosphate Biosynthetic Process Negative Regulation Of Neutrophil Apoptotic Process Common Myeloid Progenitor Cell Proliferation Inositol Phosphate Metabolic Process Positive Thymic T Cell Selection Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Ras Protein Signal Transduction Positive Regulation Of Alpha-beta T Cell Differentiation Phosphatidylinositol Phosphorylation Cellular Response To Calcium Ion
Pathways		Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Dentures ( 31235808) Eosinophil percentage of white cells ( 32888494) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Parkinson's disease ( 32201043 28892059 32310270) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		13 interacting genes: CALM1 CEP70 CTDSP1 GOLGA2 IFT88 KRT34 PPP3CA PRKACA PRKCA PSME3 SCAI TRIM54 UBQLN2
Entrez ID		3707
HPRD ID		00942
Ensembl ID		ENSG00000143772
Uniprot IDs		B2R9J0 P27987
PDB IDs
Enriched GO Terms of Interacting Partners?
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