ABCC6 and A1BG

Data Source:
BioGRID (two hybrid)

		ABCC6	A1BG
Description		ATP binding cassette subfamily C member 6	alpha-1-B glycoprotein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Secretory Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen
	Molecular Function	Transporter Activity ATP Binding ABC-type Xenobiotic Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity ATPase Activity Inorganic Diphosphate Transmembrane Transporter Activity ATPase-coupled Transmembrane Transporter Activity	Molecular_function
	Biological Process	Drug Transmembrane Transport Visual Perception ATP Transport Inorganic Diphosphate Transport Response To Drug Xenobiotic Transport Transmembrane Transport Leukotriene Transport Anion Transmembrane Transport	Platelet Degranulation Biological_process Neutrophil Degranulation
Pathways		ABC-family proteins mediated transport Defective ABCC6 causes PXE	Platelet degranulation Neutrophil degranulation
Drugs		ATP	Zinc Copper Zinc acetate
Diseases		Pseudoxanthoma elasticum, including: Pseudoxanthoma elasticum (PXE); Pseudoxanthoma elasticum-like disorder with multiple coagulation factor deficiency
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Multiple myeloma (survival) ( 26198393) Red blood cell count ( 32888494)
Interacting Genes		5 interacting genes: A1BG AK2 CRYL1 FURIN NR4A1	10 interacting genes: ABCC6 ANXA7 CDKN1A CRISP3 GRB7 PRDX4 SETD7 SMN1 SNCA TK1
Entrez ID		368	1
HPRD ID		04453	00726
Ensembl ID		ENSG00000091262	ENSG00000121410
Uniprot IDs		O95255	P04217 V9HWD8
PDB IDs		6BZR 6BZS 6NLO 6P7F
Enriched GO Terms of Interacting Partners?
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