IMPDH2 and RAD54L2

Data Source:
BioGRID (affinity chromatography technology)

		IMPDH2	RAD54L2
Description		inosine monophosphate dehydrogenase 2	RAD54 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Peroxisomal Membrane Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Nucleus
	Molecular Function	Nucleotide Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Protein Binding Metal Ion Binding	DNA Binding DNA Helicase Activity Protein Binding ATP Binding
	Biological Process	GMP Biosynthetic Process GTP Biosynthetic Process Circadian Rhythm Purine Ribonucleoside Monophosphate Biosynthetic Process Neutrophil Degranulation	DNA Duplex Unwinding
Pathways		Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis Potential therapeutics for SARS
Drugs		NADH Mycophenolate mofetil Ribavirin Mycophenolic acid Mercaptopurine Selenazole-4-carboxyamide-adenine dinucleotide 6-Chloropurine Riboside, 5'-Monophosphate Inosinic Acid VX-148
Diseases
GWAS		Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Estimated glomerular filtration rate ( 31152163)
Interacting Genes		15 interacting genes: AGR2 AKT1 ANKRD9 APIP CLK1 CPLANE2 IL1F10 IMPDH1 PIAS4 POU6F2 STAT3 SUMO2 SUMO4 TRAF2 UBQLN4	40 interacting genes: AR ATN1 ATXN1 ATXN1L BANP BHLHE40 CBX3 FAM118B HMG20A HNRNPCL1 HOMER1 IMPDH1 KIFC3 KRTAP6-3 LCE1D LCE1F NR3C1 NR5A1 NR5A2 PAICS PIAS1 POU1F1 PPARG PSMA3 RBPMS RUNX1T1 RXRA SIAH1 SQSTM1 SUMO1 SUMO2 TAX1BP1 TFAP2D THAP1 TRAF2 TRAF4 UBE2I VCX ZBTB26 ZC2HC1A
Entrez ID		3615	23132
HPRD ID		00895	10018
Ensembl ID		ENSG00000178035	ENSG00000164080
Uniprot IDs		A0A384N6C2 P12268	B3KV54 Q9Y4B4
PDB IDs		1B3O 1NF7 1NFB 6I0M 6I0O 6U8E 6U8N 6U8R 6U8S 6U9O 6UA2 6UA4 6UA5 6UAJ 6UC2 6UDO 6UDP 6UDQ
Enriched GO Terms of Interacting Partners?
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